早期乳腺癌合并钙化患者行钼靶X线检查及乳腺超声检查的诊断准确性研究

Study on the Diagnostic Accuracy of Molybdenum Target X-ray and Breast Ultrasound in Early Breast Cancer Patients with calcification

目的:探究钼靶X线检查与乳腺超声检查在早期乳腺癌合并钙化诊断中的应用价值。方法:选取2019年1月—2023年12月福建省福鼎市医院收治的82例女性乳腺癌患者作为研究对象,均接受钼靶X线检查与乳腺超声检查,探究病理结果及两种检测方法诊断效能。结果:82例患者手术病理结果显示,70例存在钙化,随着钙化数目增多,恶性概率增加,其中细杆状钙化为主要表现征象,且多为团状钙化灶分布。以病理检测结果为金标准,钼靶X线检查结果诊断出钙化60例、无钙化4例,假阴8例,假阳10例;乳腺超声检查出钙化29例,无钙化6例,假阴6例,假阳6例。钼靶X线灵敏度为85.71%、准确度为78.05%高于乳腺超声的41.43%与42.68%,差异有统计学意义(P<0.05);特异度、阴阳性预测值比较,差异无统计学意义(P>0.05)。结论:钼靶X线检查对于早期乳腺癌是否发生钙化情况具有良好的诊断效能,联合乳腺超声检查可帮助诊断假阴性病灶,有利于提高检查准确性,可为患者后续诊治提供丰富的影像学诊断依据。

Objective:To explore the application value of mammography and breast ultrasound in the diagnosis of early breast cancer with calcification.Method:82 female patients with breast cancer admitted to Fuding City Hospital in Fujian Province from January 2019 to December 2023 were selected as the study subjects,who received molybdenum target X-ray examination and breast ultrasound examination to explore pathological results and diagnostic effectiveness of detection methods.Result:The surgical pathological results of 82 patients showed that 70 cases had calcification,and as the number of calcifications increased,the probability of malignancy increased.Among them,rod-shaped calcification was the main manifestation,and most of them were distributed as clustered calcifications.Using pathological examination results as the gold standard,molybdenum target X-ray examination results diagnosed 60 cases of calcification,4 cases of no calcification,8 cases of false negative,and 10 cases of false positive.There were 29 cases of calcification detected by breast ultrasound,6 cases of no calcification,6 cases of false negative,and 6 cases of false positive.The sensitivity of molybdenum target X-ray is 85.71%,and the accuracy is 78.05%,which is significantly higher than that of breast ultrasound at 41.43%and 42.68%(P<0.05),respectively.There was no significant difference in the comparison of specificity and predicted values of yin and yang(P>0.05).Conclusion:Molybdenum target X-ray examination has a good diagnostic efficacy for whether calcification occurs in early breast cancer.Combining with breast ultrasound examination,it can help diagnose false negative lesions,improve the accuracy of examination,provide rich imaging diagnostic basis for follow-up diagnosis and treatment of patients,and can be further popularized in clinical use.