孟鲁司特钠联合盐酸西替利嗪及布地奈德雾化治疗小儿咳嗽变异性哮喘的价值

Value of Montelukast Sodium Combined with Cetirizine Hydrochloride and Budesonide Nebulization in the Treatment of Cough Variant Asthma in Children

目的:观察孟鲁司特钠联合盐酸西替利嗪及布地奈德雾化治疗小儿咳嗽变异性哮喘(CVA)的效果。方法:选择2021年1月—2023年6月商河县人民医院诊治的82例CVA患儿作为研究对象,以摸球法将其分为研究组与对比组,各41例。对比组采取盐酸西替利嗪及布地奈德雾化治疗,研究组在对照组基础上加用孟鲁司特钠治疗,对比两组治疗效果、肺功能、免疫功能。结果:研究组治疗总有效率为95.12%,高于对比组的80.49%,差异有统计学意义(χ^(2)=4.100,P=0.043);研究组治疗后肺功能、免疫功能优于对比组,差异有统计学意义(P<0.05)。结论:小儿CVA采用孟鲁司特钠联合盐酸西替利嗪及布地奈德雾化治疗,可以提高治疗效果,促进肺功能恢复,还有助于提高免疫功能。

Objective:To observe the effect of Montelukast Sodium combined with Cetirizine Hydrochloride and Budesonide nebulization in the treatment of cough variant asthma(CVA)in children.Method:A total of 82 children with CVA who treated in Shanghe County People's Hospital from January 2021 to June 2023 were selected as the study objects,they were divided into the study group and the control group by touching the ball method,41 cases in each group.The control group was treated with Cetirizine Hydrochloride and Budesonide nebulization,and the study group was treated with Montelukast Sodium on the basis of the control group,and the treatment effect,lung function and immune function of two groups were compared.Result:The total effective rate of treatment in the study group was 95.12%,which was higher than 80.49%in the control group,the difference was statistically significant(χ^(2)=4.100,P=0.043);the lung function and immune function of the study group after treatment were better than those of the control group,the differences were statistically significant(P<0.05).Conclusion:Montelukast Sodium combined with Cetirizine Hydrochloride and Budesonide nebulization in the treatment of CVA in children can improve treatment effect,promote lung function recovery,and also help improve immune function.