国内外短缺药品的文献计量学分析

Bibliometric Analysis of Shortage Drugs at Home and Abroad

目的为我国短缺药品监管提供参考。方法检索中国知网、万方、维普及Web of Science数据库,获取国内外短缺药品研究现状相关文献,导入CiteSpace 6.2软件进行可视化,分析并比较国内、国外短缺药品监管研究现状及发展动态。结果共获得文献3081篇,其中国内文献553篇、英文文献2528篇,发文量分别以2019年至2020年和2020年至2022年较高,国内文献数量增长趋势较明显。国内以方宇、杨世民、杨才军等为核心作者,以中国药科大学为最高产机构(21篇);国外作者发文量以FOX和ATALA最多(均为11篇),国外机构发文量以Massachusetts Gen Hosp与Harvard Med Sch最多(均为36篇);国内、国外作者和研究机构合作网络均较分散,研究机构以高校和研究所为主。国内相关研究形成了短缺药品、药品短缺、供应保障等关键词聚类,国外相关研究形成了regenerative medicine,tissue engineering,machine learning等关键词聚类。短缺药品的供应保障是目前该领域的研究重点。结论当前国内短缺药品相关研究势头良好,应进一步结合我国国情,借鉴国外短缺药品监管方法,重视定量分析,运用经济学理论提出更完善的应对策略,切实解决我国的药品短缺问题。

Objective To provide a reference for the regulation of shortage drugs in China.Methods The relevant studies on the research status of shortage drugs at home and abroad in the databases such as CNKI,WanFang,VIP and Web of Science were searched and imported into the CiteSpace 6.2 software for visualization analysis,the research status and development trend of shortage drug regulation at home and abroad were compared.Results A total of 3081 studies were obtained,of which 553 were in Chinese and 2528 were in English.The quantity of publications was larger from 2019 to 2020(for Chinese studies)and from 2020 to 2022(for English studies),with a more obvious growth in Chinese studies.Fang Yu,Yang Shimin,Yang Caijun and so on were the core authors,while the China Pharmaceutical University was the most productive institution(21 studies)in China.FOX and ATALA were the foreign authors publishing most studies(11 studies),while Massachusetts Gen Hosp and Harvard Med Sch were the most productive foreign institutions(36 studies).The cooperative networks of domestic and foreign authors with research institutions were relatively scattered,with universities and institutes being the main research institutions.The keyword clusters such as shortage drugs,drug shortage,and supply guarantee(Chinese)were formed in domestic relevent researches,while those such as regenerative medicine,tissue engineering and machine learning were formed in foreign relevent researches.The supply guarantee of shortage drugs is currently a research focus in this field.Conclusion Currently,there is a good development trend in researches related to the shortage drugs in China.Based on China′s national conditions and foreign regulation for shortage drugs,we should pay attention to quantitative analysis,propose more comprehensive response strategies by economic theories to effectively solve the problems of drug shortage in China.