失代偿期肝硬化患者肌少症的研究进展

Research Progress of Sarcopenia in Decompensated Liver Cirrhosis

肌少症在肝硬化患者中普遍存在,尤其在失代偿期肝硬化中,其存在预示着严重的不良后果,因此早期识别和及早干预尤为重要。截至目前,关于肝硬化肌少症的相关研究文献,未明确区分失代偿与代偿期肝硬化患者。因此,本研究重点从失代偿期肝硬化患者肌少症的发病机制进行综述,同时探讨其治疗现状,以期提高肝病医生对肝硬化肌少症的认识,重视其临床干预以改善患者的预后。

Sarcopenia is common in patients with cirrhosis,especially in decompensated cirrhosis.Its presence can predict serious adverse outcomes,so early identification and timely intervention are important.So far,the relevant literature on sarcopenia of cirrhosis has not been clearly differentiated between patients with decompensated and compensated cirrhosis.Therefore,the pathogenesis of sarcopenia in patients with decompensated cirrhosis is reviewed,and its current treatment status is explored.Clinical intervention should be emphasized to improve the prognosis of patients with Sarcopenia in liver cirrhosis.