β受体阻滞剂在心衰患者中的应用进展

Progress in the use ofβ-blockers in patients with heart failure

心力衰竭(心衰)是心血管内科较为常见的循环功能障碍的一类综合征,治疗药物包括利尿剂、血管紧张素转化酶抑制剂(ACEI)类药物等,达到降低心脏负担、利尿消肿、增强心肌收缩力等目的。随着对心衰的不断研究,β受体阻滞剂在心衰的临床治疗中已成为较为常见的药物,对于最初β受体阻滞剂的争议性限制应用,后期多个大规模医学试验为β受体阻滞剂在心衰治疗中提供有力依据。为了进一步研究β受体阻滞剂在心衰的临床使用现状和安全性,本文对近年来应用β受体阻滞剂治疗心衰的进展进行如下综述。

Heart failure is a kind of syndrome of circulatory dysfunction that is more common in cardiovascular medicine.Treatment drugs include diuretics,angiotesion converting enzyme inhibitors(ACEI)drugs,etc.,thus to achieve the purpose of reducing the heart burden,reducing diuretic swelling,and enhancing myocardial contractility.With the continuous research on heart failure,β-blockers have common in the clinical treatment of heart failure.For the controversial limited application ofβ-blockers at the initial stage,multiple large-scale medical trials in the later stage provide a strong basis forβ-blockers in the treatment of heart failure.In order to further study the clinical use and safety ofβ-blockers in heart failure,this article reviews the progress ofβ-blockers in the treatment of heart failure in recent years.