角膜塑形镜控制近视的临床研究进展

Advances in clinical research on the control of myopia with orthokeratology

角膜塑形镜(OK镜)控制近视进展是目前近视防控的重要手段之一。近年来随着角膜塑形镜材料和设计的持续革新,其有效性与安全性在多项研究中得到广泛验证。研究显示,角膜塑形镜在控制近视进展中效果显著,尤其中度近视儿童更佳。该方法不仅能有效减缓眼轴增长,对调节功能也有积极影响,但亦存在对视觉质量产生一定影响的潜在风险。因此,在选择镜片设计和患者适配性时,需权衡视觉质量与近视控制效果,力求最佳平衡。尽管角膜塑形镜在近视防控中取得了显著进展,但关于其长期控制效果的稳定性、对视觉质量影响的程度与机制等仍存在争议。同时,其与其他近视防控手段的联合应用展现出增强效应的潜力。然而,关于停用后的近视反弹情况,仍需要更多临床数据支持。文章旨在对角膜塑形镜的设计、近视进展控制的有效性、安全性及联合应用等方面进行全面综述。

Orthokeratology(OK lens)is considered to be one of the most effective optical treatments for myopia control.Its safety and efficiency in controlling myopia progression have been rigorously verified by numerous studies.As the materials and technology of lens have evolved,orthokeratology has demonstrated remarkable results in myopia control,particularly among children with moderate myopia.Not only does orthokeratology effectively decelerate axial length growth,but it also positively impacts regulatory function.However,it is crucial to acknowledge that there may be some compromise in visual quality.Therefore,the perfect balance between lens design and patient adaptability must be considered to maintain visual clarity and optimize myopia control.While orthokeratology has made significant strides in myopia control,there are still lingering questions about its long-term stability,the precise impact of visual quality,and the others.Furthermore,combining orthokeratology with other strategies offers better effects.Nevertheless,further clinical data is needed to estimate the rebound effects of withdrawal.This review summarizes the technology,safety,efficacy and combination therapy of orthokeratology on myopia control.