弥散张量成像、体素内不相干运动及改良Dixon水脂分离技术用于评估糖尿病肾病研究进展

Research progresses of diffusion tensor imaging,intravoxel incoherent motion and modified Dixon water-fat separation techniques for evaluating diabetic nephropathy

糖尿病肾病(DN)是由糖尿病引起的主要微血管并发症之一。功能MRI(fMRI)敏感且无创,可评估早期DN的肾皮质和肾髓质损伤,揭示DN早期肾皮质和肾髓质灌注异常和分子扩散变化。本文就弥散张量成像(DTI)、体素内不相干(IVIM)及改良Dixon水脂分离技术用于评估DN的研究进展进行综述。

Diabetic nephropathy(DN)is one of the major microvascular complications caused by diabetes.Functional MRI(fMRI)techniques are sensitive and non-invasive,which can assess renal cortex and medullary damage in early DN,and reveal renal cortex and medullary perfusion abnormalities and molecular diffusion changes in early DN.The research progresses of diffusion tensor imaging(DTI),intravoxel incoherent motion(IVIM)and modified Dixon water-fat separation techniques for evaluating DN were reviewed in this article.