重症社区获得性肺炎患者发生心力衰竭危险因素的分析

Risk factors of heart failure in patients with severe community-acquired pneumonia

目的:探讨重症社区获得性肺炎患者(severe community-acquired pneumonia,SCAP)发生心力衰竭(heart failure,HF)的危险因素。方法:回顾性收集2021年11月至2023年5月,河北中石油中心医院住院治疗的SCAP 113例患者,合并心力衰竭为病例组(n=53)及未出现HF对照组(n=60)。比较两组患者住院期间的临床资料、超声检查参数、实验室参数间的差异,并将P<0.05的变量纳入多因素Logistic回归模型,评估SCAP患者发生HF的危险因素。结果:纳入53例病例组和60例对照组患者,多因素Logistic回归分析显示,冠心病(OR=3.64,95%CI:1.26~10.53,P=0.02)、心律失常(OR=5.66,95%CI:1.72~18.66,P=0.01)、急性心肌梗死(OR=3.72,95%CI:1.52~9.12,P=0.004)、使用有创呼吸机(OR=3.36,95%CI:1.13~9.98,P=0.03)是SCAP患者发生HF的危险因素。结论:冠心病、心律失常、急性心肌梗死、使用有创呼吸机是SCAP患者发生HF的危险因素。

Objective:To investigate the risk factors for heart failure(HF)in severe communityacquired pneumonia(SCAP).Methods:SCAP 113 patients hospitalized in Hebei CNPC Central Hospital from November 2021 to May 2023 were retrospectively collected.They were divided into the case group(n=53)and the control group without HF(n=60).The differences of clinical data,ultrasonic parameters and laboratory parameters during hospitalization were compared between the two groups,and P<0.05was compared.Multivariate Logistic regression model was used to evaluate the risk factors for HF in SCAP patients.Results:Multivariate Logistic regression analysis showed that coronary heart disease(OR=3.64,95%CI 1.26~10.53,P=0.02),arrhythmia(OR=5.66,95%CI:1.72~18.66,P=0.01),acute myocardial infarction(OR=3.72,95%CI:1.52~9.12,P=0.004),invasive ventilator(OR=3.36,95%CI:1.13~9.98,P=0.03)were risk factors for HF in patients with SCAP(P<0.05).Conclusions:Coronary heart disease,arrhythmia,acute myocardial infarction,and invasive ventilator use is a risk factor for HF in patients with SCAP.