观察机械辅助通气在ICU急性左心衰竭患者抢救中的临床疗效

Observation on the clinical efficacy of assisted mechanical ventilation in ICU patients with acute left heart failure

目的分析重症加强护理病房(ICU)急性左心衰竭患者使用机械辅助通气进行抢救的效果。方法选择104例ICU急性左心衰竭患者,通过随机抽样法分为常规组、研究组,各52例。常规组采用单纯药物治疗,研究组在常规组基础上采用机械辅助通气治疗。比较两组抢救结果、抢救满意度、心功能指标、呼吸频率、心率、动脉血气指标及不良事件发生率。结果研究组抢救总有效率为98.08%,高于常规组的82.69%,差异性具有统计学价值(P<0.05)。研究组抢救总满意度为96.15%,高于常规组的80.77%,差异性具有统计学价值(P<0.05)。两组不良事件发生率对比,差异性并无统计学价值(P>0.05)。研究组治疗后左室收缩末期内径(33.34±1.56)mm、左室舒张末期内径(38.04±2.01)mm小于常规组的(40.32±1.62)、(46.39±2.23)mm,左室射血分数(54.35±2.37)%大于常规组的(49.23±2.26)%,差异性具有统计学价值(P<0.05)。研究组治疗后呼吸频率(18.14±1.32)次/min、心率(71.21±8.43)次/min、动脉血氧分压(94.76±11.45)mm Hg(1 mm Hg=0.133 kPa)、动脉血二氧化碳分压(38.23±2.12)mm Hg、pH值(7.97±0.46)均优于常规组的(20.24±2.56)次/min、(83.78±11.56)次/min、(88.12±11.05)mm Hg、(44.24±2.45)mm Hg、(7.56±0.58),差异性具有统计学价值(P<0.05)。结论为ICU急性左心衰竭患者使用机械辅助通气和药物进行治疗,可以有效改善患者心功能指标及动脉血气相关指标,疗效显著,临床应用价值较高。

Objective To analyze the effect of assisted mechanical ventilation in intensive care unit(ICU)patients with acute left heart failure.Methods A total of 104 ICU patients with acute left heart failure were selected and divided into a conventional group and a study group by random sampling method,with 52 cases in each group.The conventional group was treated with simple drug therapy,and the study group was treated with assisted mechanical ventilation based on the conventional group.The rescue results,rescue satisfaction,cardiac function index,respiratory rate,heart rate,arterial blood gas index and the incidence of adverse events were compared between the two groups.Results The total effective rate of the study group was 98.08%,which was higher than 82.69%of the conventional group,and the difference was statistically valuable(P<0.05).The total rescue satisfaction of the study group was 96.15%,which was higher than 80.77%of the conventional group,and the difference was statistically valuable(P<0.05).There was no statistical difference in incidence of adverse events between the two groups(P>0.05).After treatment,the left ventricular end-systolic diameter of(33.34±1.56)mm and the left ventricular end-diastolic diameter of(38.04±2.01)mm in the study group were smaller than(40.32±1.62)and(46.39±2.23)mm in the conventional group;the left ventricular ejection fraction of(54.35±2.37)%in the study group was higher than(49.23±2.26)%in the conventional group;the difference was statistically valuable(P<0.05).After treatment,the respiratory rate of the study group was(18.14±1.32)times/min,the heart rate was(71.21±8.43)beats/min,the arterial partial pressure of oxygen was(94.76±11.45)mm Hg(1 mm Hg=0.133kPa),the arterial partial pressure of carbon dioxide was(38.23±2.12)mm Hg and pH was(7.97±0.46),which were better than(20.24±2.56)times/min,(83.78±11.56)beats/min,(88.12±11.05)mm Hg,(44.24±2.45)mm Hg and(7.56±0.58)of the conventional group.The difference was statistically valuable(P<0.05).Conclusion The use of assisted mechanical ventilation and drug therapy for ICU patients with acute left heart failure can effectively improve the cardiac function indexes and arterial blood gas-related indexes of the patients,with remarkable therapeutic effects and high clinical application value.