傅里叶变换在微剂量探测器组织等效换算中的应用

Tissue equivalent conversion of microdosimeters by Fourier transform

金刚石微剂量探测器被认为是放射生物学效应研究中最有前景的探测器之一。然而,由于金刚石与生物组织的密度不同,同等大小金刚石微剂量探测器与生物组织中的沉积能量分布并不相同。本研究围绕金刚石与相同大小生物组织中沉积能量分布的等效换算展开研究,结合沉积能量分布数学模型和傅里叶变换相关性质提出了一种等效换算方法。研究结果显示:该方法在同等大小金刚石与生物组织的等效换算中有较好的效果,但该换算方法的适用性会受到沉积能量分布数学模型适用范围的影响。因此,如果能够建立适用于描述不同条件下介质中辐射沉积能量分布的数学模型,将有助于提高该换算方法的适用范围。

Diamond is considered a promising detector in radiobiological studies.However,the difference in densities between diamond and tissue imply that their energy deposition spectra are not identical,even for diamond and tissues of the same size.The energy deposition spectrum in diamond was converted to match a tissue sample of the same size.A method based on a mathematical model of energy deposition distribution and the Fourier transform was proposed.The results indicate that the spectra converted from diamond to tissue align closely with those of the tissue.Nevertheless,the applicability of this method is constrained by the mathematical model of energy deposition distribution.Thus,developing a mathematical model that describes the energy deposition spectrum under various conditions can enhance the applicability of this conversion method.