前庭诱发肌源性电位对前庭性偏头痛的应用研究

Application research of vestibular evoked myogenic potentials on patients with vestibular migraine

目的通过前庭诱发肌源性电位(VEMPs)评价前庭性偏头痛(VM)患者的椭圆囊、球囊、前庭上神经通路以及前庭下神经通路的功能状况,探讨其临床应用价值。方法参照VM的诊断标准,选取36例VM患者作为VM组,同时选取36例健康体检者作为对照组,采用前瞻性对照研究的方法,对两组个体分别进行颈肌前庭诱发电位(cVEMP)和眼肌前庭诱发电位(oVEMP)检查,对其相关指标进行比较分析。结果与对照组相比,VM组cVEMP的引出率和潜伏期无明显差异,但其波幅明显降低,耳间不对称比明显升高。结论VM患者的椭圆囊和前庭上神经通路出现不同程度的功能障碍,oVEMP可作为其确诊的重要检查手段。

Objective To evaluate the functional status of utricle,saccule,superior vestibular pathway and inferior vestibular pathway in patients with vestibular migraine by means of vestibular evoked myogenic potentials,and to explore its clinical value.Methods According to the diagnostic criteria of vestibular migraine(VM),we chose 36 patients of vestibular migraine as the VM group.At the same time,36 healthy subjects were selected as the control group.The prospective control study was used to examine all subjects of two groups in ocular evoked myogenic potential and cervical evoked myogenic potential,and the indexes of vestibular evoked myogenic potentials were compared and analyzed.Results There was no obvious differences in emissions and latencies of cervical evoked myogenic potential between the VM group and the control group,however,the patients of the VM group showed lower amplitudes and higher inter aural asymmetry ratio of cervical evoked myogenic potential.Conclusion There were significant dysfunctions in utricle and the superior vestibular pathway in patients with vestibular migraine,and oVEMP could be an important way for the diagnosis of VM.