卵巢成熟性囊性畸胎瘤恶性转化一例

Malignant Transformation of Mature Cystic Teratoma of Ovary:A Case Report

卵巢成熟性囊性畸胎瘤(mature cystic teratoma of ovary,MCTO)是最常见的卵巢生殖细胞肿瘤,通常为良性,然而在极少数情况下,其可能发生恶性转化(malignant transformation,MT)。MT-MCTO多见于绝经后期女性,由于其罕见性,目前尚缺乏标准的诊治方案。报告1例77岁MT-MCTO为鳞状细胞癌ⅡB期患者的诊治过程,该患者在经肿瘤细胞减灭术后接受1个疗程博来霉素+依托泊苷+顺铂方案化疗。然而,由于患者身体情况无法耐受进一步治疗,随访术后半年死亡。

Mature cystic teratoma of ovary(MCTO) is the most common ovarian germ cell tumor,which is usually benign.However,in rare cases,it may undergo malignant transformation.Malignant transformation of MCTO(MT-MCTO) is common in postmenopausal women.Due to its rarity,there is still no standard diagnosis and therapeutic options.This paper reports the diagnosis and treatment of a 77-year-old patient with MT-MCTO to squamous cell carcinoma at stage ⅡB.After cytoreductive surgery,the patient received a course of chemotherapy with bleomycin +etoposide +cisplatin.However,because the patient ′ s physical condition could not tolerate further treatment,the patient died after six months of postoperative follow-up.