用于骨组织再生的电活性高分子材料研究进展

Research progress in electroactive polymer materials for bone tissue regeneration

天然骨组织具有压电特性,重建缺损部位的局部电微环境是刺激骨再生的有效策略。电活性高分子材料能够仿生骨组织压电特性,修复缺损处生理学电微环境,进而促进骨组织再生修复。本文分类介绍了几种类型的电活性高分子材料,包括导电高分子、压电高分子和驻极体高分子材料,概述了其在骨组织修复领域的研究进展,并分析了不同材料的优势与挑战。

Natural bone tissue has piezoelectric properties,and reconstruction of the local electrical microenvironment at the defect site is an effective strategy to stimulate bone regeneration.Using electroactive polymer materials to prepare bone tissue engineering scaffolds can imitate the piezoelectric properties of bone tissue,repair the physiological electrical microenvironment at the defect,and then promote bone tissue regeneration and repair.This article categorized and intro⁃duced several types of electroactive polymer materials,including conductive polymers,piezoelectric polymers,and elec⁃tret polymer materials.It summarized their research progress in the field of bone tissue repair and analyzed the advantag⁃es and challenges of different materials.