急性心力衰竭患者炎症因子与其预后的相关性分析

Correlation between inflammatory factors and their prognosis in patients with acute heart failure

目的:探讨急性心力衰竭患者炎症因子与其预后的相关性分析。方法:对我院2019年4月至2022年2月间141例AHF患者进行1年随访,分析血清指标对预后情况的相关性。结果:AHF患者死亡率为31.91%,生存率为68.08%。联合检测血小板吸附蛋白2(TSP-2)、B型利钠肽(BNP)及血清胱抑素C(Cys-C)水平对AHF患者预后的价值最高,其AUC为0.878。结论:检测血清中的TSP-2、BNP和Cys-C水平,对辅助诊断急性心力衰竭(AHF)及评估其预后具有重大价值,有助于为患者制定更加精准的治疗方案。

Objective:This study aims to explore the correlation between inflammatory markers and the prognosis of patients with acute heart failure(AHF).Methods:A one-year follow-up was conducted on 141 AHF patients at our hospital from April 2019 to February 2022.The correlation between serum markers and patient prognosis was analyzed.Results:The mortality rate among AHF patients was 31.91%,with a survival rate of 68.08%.The combination of Thrombospondin-2(TSP-2),B-type natriuretic peptide(BNP),and serum cystatin C(Cys-C)provided the highest value for predicting AHF patient outcomes,with an area under the curve(AUC)of 0.878.Conclusion:The combined measurement of serum TSP-2,BNP,and Cys-C levels has significant value in assisting with the diagnosis of acute heart failure and assessing patient prognosis.This approach may help in formulating more precise treatment plans for AHF patients.