超声在脑深部肿瘤治疗中的应用进展

Application progress of ultrasound in the treatment of deep brain tumor

脑深部肿瘤是指生长于三脑室、松果体区、鞍区等深部结构处的肿瘤,周围毗邻重要神经、血管结构,手术难度高,术后并发症多,其治疗往往是以手术为主辅以放化疗的综合治疗。超声不仅可以识别肿瘤的大小、形状、位置和深度,帮助医师更精确地定位和切除肿瘤,减少手术损伤,还可以辅助肿瘤治疗药物跨越血脑屏障进入靶向部位,甚至直接消融肿瘤。本文主要从非手术应用和手术应用两方面综述超声在脑深部肿瘤治疗中的应用进展。

Deep brain tumor refers to the tumor growing in the deep structure of the third ventricle,pineal region,sella region and so on,which is adjacent to important nerve and vascular structures.The operation is difficult and postoperative complications are frequent,and its treatment is usually based on surgery and combined with radiotherapy and chemotherapy.Ultrasound can not only be used to identify the size,shape,location and depth of the tumor,help physicians locate and remove the tumor more accurately,reduce the trauma and injury of surgery,but also assist tumor therapy drugs to cross the blood-brain barrier into the targeted site,or even directly ablate the tumor.This article mainly reviews the auxiliary role of ultrasound in the treatment of deep brain tumor from the aspects of non-surgical application and surgical application.