心脏磁共振特征追踪技术评估自身免疫性风湿病心肌应变的研究进展

Research progress of cardiac magnetic resonance feature tracking technique in evaluating myocardial strain in autoimmune rheumatic diseases

自身免疫性风湿病(autoimmune rheumatic diseases,ARDs)是一类由于机体免疫系统异常活化,引起由抗原抗体复合物介导的炎症反应,造成多系统损害的全身性疾病。心血管系统常受累及,长期的炎症反应引起心肌纤维化和心肌重构,导致患者预后不良。影像学检查可为ARDs患者心脏受累提供可靠依据,心脏磁共振特征追踪(cardiac magnetic resonance feature tracking,CMR-FT)技术能够定量评估心肌应变,在识别心肌损害、评估严重程度及预后方面具有重要临床价值。本文阐述了CMR-FT技术的原理以及在评估各类ARDs患者心血管受累中的应用价值,并对现有研究的进展、局限性以及未来的改进措施进行总结,旨在将CMR-FT技术投入临床实际应用中,为ARDs患者提供更可靠的影像检查。

Autoimmune rheumatic diseases(ARDs)are characterized by abnormal activation of the body's immune system,resulting in an inflammatory reaction mediated by antigen-antibody complexes and causing damage to multiple systems as a systemic disease.These diseases frequently involve the cardiovascular system,and long-term inflammatory reaction causes myocardial fibrosis and myocardial remodeling,which ultimately results in poor prognosis for patients.Imaging examinations can provide reliable evidence of cardiac involvement in patients with ARDs.Cardiac magnetic resonance feature tracking(CMR-FT)technology enables quantitative evaluation of myocardial strain,thus playing an important clinical role in recognizing myocardial damage and assessing its severity and prognosis.The present article provided an in-depth explanation of the principle and application value of CMR-FT technology in evaluating cardiovascular involvement in patients with ARDs.Additionally,it summarized the progress made in existing research,highlights limitations,and proposes future improvement measures.The ultimate goal is to integrate CMR-FT technology into clinical practice and provide more reliable imaging for patients with ARDs.