顺序追踪联合彩色多普勒超声诊断胎儿畸形的研究

Study on diagnosis of fetal malformation by sequential trackingcombined color Doppler ultrasonography

目的探讨连续顺序追踪超声联合彩色多普勒超声诊断产前胎儿肢体畸形的优势。方法将329名孕妇为研究对象,均接受连续顺序追踪超声检查和彩色多普勒超声检查,以胎儿出生及引产结果的金标准为依据,对比分析连续顺序追踪超声检查和彩色多普勒超声检查两者分别诊断胎儿肢体畸形的灵敏度与两者联合诊断的灵敏度和差异。结果连续顺序追踪超声联合彩色多普勒超声诊断产前胎儿肢体畸形的准确度、灵敏度、特异度、阳性预测值均高于任何一种单一超声诊断方式,差异有统计学意义(P<0.05)。结论彩色多普勒联合连续顺序追踪超声与胎儿出生及引产结果一致(Kappa=0.85)。提示连续顺序追踪超声联合彩色多普勒超声用于诊断产前胎儿肢体畸形,优于单一超声法诊断。

Objective To explore the advantages of continuous sequential tracking combined with color Doppler ultrasound in the diagnosis of prenatal fetal limb malformation.Methods In this paper,329 pregnant women were described as study subjects,all of them underwent continuous sequential tracking ultrasound and color Doppler ultrasound.Based on the gold standard of fetal birth and induced labor results,compared and analyzed examination sensitivity by continuous sequential tracking method and color Doppler ultrasound,respectively,and examination sensitivity and difference by continuous sequential tracking method combined with color Doppler ultrasound in the diagnosis of fetal limb malformation.Results The accuracy,sensitivity,specificity and positive predictive value of continuous sequential tracking method combined with color Doppler ultrasound in the diagnosis of fetal limb malformation were higher than any single ultrasonic diagnosis method,and the difference was statistically significant(P<0.05).High consistency between the results of color Doppler ultrasound combined with continuous sequential tracking method and fetal birth and induction of labor(Kappa-0.85).Conclusions It is suggested that continuous sequential tracking combined with color Doppler ultrasonography is superior to single ultrasonography in the diagnosis of prenatal fetal limb malformation.