调肝和胃针刺法治疗胃食管反流病(肝胃郁热证)临床疗效研究

Clinical efficacy of liver soothing and stomach benefitingacupuncture in the treatment of gastroesophageal reflux disease

观察调肝和胃针刺法治疗胃食管反流病(肝胃郁热证)的临床疗效。方法:将符合纳入标准的70名患者随机均分为治疗组与对照组,最终符合疗效分析者共66例,其中治疗组33例,对照组33例。对照组采用艾司奥美拉唑镁肠溶片进行基础治疗,治疗组在基础治疗的基础上加调肝和胃针刺法治疗。以烧心、反酸主症,中医症候及生活质量等为观察指标,评价其疗效和安全性。结果:①治疗后两组患者烧心、反酸主症均得到改善(均P<0.05),且在改善的程度上治疗组优于对照组(P<0.05)。②治疗组治疗后烧心、反酸、胸骨后疼痛、胃脘灼痛、脘腹胀满、嗳气呃逆等中医症候均得到改善(均P<0.05);对照组治疗后烧心、胸骨后疼痛得到改善(均P<0.05),而反酸、胃脘灼痛、脘腹胀满、嗳气呃逆则改善不明显(均P>0.05);治疗后患者烧心、反酸、脘腹胀满的改善程度,治疗组优于对照组(均P<0.05)。③治疗后两组患者生活质量得到改善,但改善的程度组间无差异(P>0.05)。④中医症候疗效:治疗组总有效率87.87%,对照组60.60%。治疗组的总有效率优于对照组(P<0.05)。结论:调肝和胃针刺法治疗胃食管反流病(肝胃郁热证),能够提高单用艾司奥美拉唑镁治疗的临床疗效。

To observe the clinical efficacy of liver regulating and stomach acupuncture methods in the treatment of gastroesophageal reflux disease(liver stomach stagnation heat syndrome).Method:70patients who met the inclusion criteria were randomly divided into a treatment group and a control group.A total of 66patients met the efficacy analysis criteria,including 33in the treatment group and 33in the control group.The control group received basic treatment with esomeprazole magnesium enteric coated tablets,while the treatment group received additional liver and stomach acupuncture on the basis of basic treatment.Evaluate the efficacy and safety of heartburn,acid reflux,traditional Chinese medicine symptoms,and quality of life as observation indicators.Result:①After treatment,the main symptoms of heartburn and acid reflux in both groups of patients were improved(both P<0.05),and the degree of improvement in the treatment group was better than that in the control group(P<0.05).②After treatment,traditional Chinese medicine symptoms such as heartburn,acid reflux,sternal pain,epigastric burning pain,epigastric distension,belching and hiccup improved in the treatment group(all P<0.05);The control group showed improvement in heartburn and sternal pain after treatment(all P<0.05),while acid reflux,epigastric burning pain,epigastric distension,belching and hiccup did not show significant improvement(all P>0.05);The improvement of heartburn,acid reflux,and abdominal distension in patients after treatment was better in the treatment group than in the control group(all P<0.05)After treatment,the quality of life of the two groups of patients improved,but there was no difference in the degree of improvement between the groups(P>0.05)Traditional Chinese medicine syndrome efficacy:The total effective rate of the treatment group is 87.87%,while the control group is 60.60%.The total effective rate of the treatment group was better than that of the control group(P<0.05).Conclusion:The liver regulating and stomach acupuncture methods can improve the clinical efficacy of using esomeprazole magnesium alone in the treatment of gastroesophageal reflux disease(liver stomach stagnation heat syndrome).