摘要
结合"细环病毒载量在中国肾移植受者免疫抑制治疗中的动力学变化:多中心前瞻性观察性双盲队列研究"具体策划和实施过程中的经验与教训,探讨研究者发起的肾移植多中心前瞻性临床研究在我国的发展现状与主要困难,并就相关研究组织设计与实施流程管理过程中需要注意的问题进行讨论,以提高相关研究的实施质量。
Based upon the experiences of planning and implementation of"Dynamic changes of Torque Teno virus load in Chinese renal transplant recipients with immunosuppressive therapy:A multi-center prospective observational double-blind cohort study",this article explored the current status and major difficulties of investigator-initiated multi-center prospective clinical trials of kidney transplantation in China.Various issues of organization design and implementation process management were discussed for enhancing the quality of implementing the relevant trials.
作者
王思君
陈慧俊
匡培丹
吴晴航
胡梦娜
陈刚
张雷
朱兰
Wang Sijun;Chen Huijun;Kuang Peidan;Wu Qinghang;Hu Mengna;Chen Gang;Zhang Lei;Zhu Lan(Institute of Organ Transplantation,Affiliated Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Key Laboratory of Organ Transplantation,Ministry of Education,NHC Key Laboratory of Organ Transplantation,Key Laboratory of Organ Transplantation,Chinese Academy of Medical Sciences,Wuhan 430030,China;Department of Organ Transplantation,First Affiliated Hospital,Naval Medical University,Shanghai 200433,China;Department of Kidney Transplantation,First Affiliated Hospital,Xi'an Jiaotong University School of Medicine,Xi'an 710061,China;Center of Nephrology,First Affiliated Hospital,College of Medicine,Zhejiang University,Hangzhou 310003,China;Organ Transplantation Center,Institute of Urology,West China Hospital,Sichuan University,Chengdu 610044,China)
出处
《中华器官移植杂志》
CAS
2024年第7期476-480,共5页
Chinese Journal of Organ Transplantation
基金
中国医学科学院中央级公益性科研院所基本科研业务费专项(2023-PT320-07)。
关键词
肾移植
多中心临床研究
前瞻性研究
研究者发起的临床研究
Kidney transplantation
Multi-center clinical trial
Prospective study
Investigator-initiated clinical trial
