非呼吸机相关医院获得性肺炎预防策略的最佳证据总结

Summary of best evidence on prevention strategies for non-ventilator associated hospital-acquired pneumonia

目的总结非呼吸机相关医院获得性肺炎预防策略的最佳证据。方法检索UpToDate、BMJ Best Practice、美国国立指南库、国际指南协作网、医脉通、PubMed、Web of Science、Cochrane Library、万方数据库、中国生物医学文献数据库等数据库和网站中非呼吸机相关医院获得性肺炎感染防控的相关文献,检索时限为2013年11月1日—2023年11月1日。由2名研究小组成员进行文献质量评价、提取证据。结果共纳入10篇文献,包括6篇指南、2篇系统评价和2篇随机对照试验,从口腔清洁、预防误吸、营养与活动、气道管理、手卫生、清洁消毒与隔离、抗生素管理7个方面汇总了26条证据。结论本研究总结了非呼吸机相关医院获得性肺炎预防策略的最佳证据,为医护人员进行非呼吸机相关医院获得性肺炎的预防与控制提供参考。

Objective To summarize the best evidence of prevention strategies for non-ventilator associated hospital-acquired pneumonia(NV-HAP).Methods The literature on the prevention and control of NV-HAP was searched on UpToDate,BMJ Best Practice,Agency for Healthcare Research and Quality,Guidelines International Network,Medlive,PubMed,Web of Science,Cochrane Library,WanFang Data,China Biology Medicine disc,and other databases and websites.The search period was from November 1,2013,to November 1,2023.Two researchers conducted a literature quality evaluation and extracted evidence.Results A total of ten articles were included,including six guidelines,two systematic reviews,and two randomized controlled trials.Twenty-six pieces of evidence were summarized from seven aspects of oral hygiene,prevention of aspiration,nutrition and activity,airway management,hand hygiene,cleaning,disinfection and isolation,and antibiotic management.Conclusions The best evidence of NV-HAP prevention strategies summarized provides a reference for medical and nursing staff to prevent and control NV-HAP.