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2020年湖北省成年人高尿酸血症监测分析

Surveillance for hyperuricemia in adults in Hubei,2020
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摘要 目的探究2020年湖北省成年人高尿酸血症(HUA)的患病情况及危险因素,为针对性地开展人群干预提供科学依据。方法提取“湖北省2020年慢性病及危险因素调查项目”基线调查中年龄、性别、文化程度、吸烟情况、饮酒量、身体活动情况、血糖、血压、血脂、血尿酸、身高、体质量、腰围等数据变量,经处理后采用χ^(2)检验和多因素logistic回归分析HUA的危险因素。结果本次调查共纳入湖北省18岁以上常住居民19208人,HUA粗患病率为9.36%,经加权调整后的患病率为11.10%。患病率与年龄呈正相关(趋势χ^(2)=10.788,P<0.001),男性粗患病率(19.05%)高于女性粗患病率(3.04%)(χ^(2)=1388.143,P<0.001);城乡之间患病率比较,差异无统计学意义(χ^(2)=0.822,P>0.050)。非条件多因素logistic回归分析显示,年龄、性别、高血压、体质指数、中心性肥胖、危险饮酒和有害饮酒、血脂异常是患HUA的影响因素。45~59岁年龄组[比值比(OR)=0.75,95%置信区间(CI):0.65~0.86]、女性(OR=0.13,95%CI:0.12~0.15)、低体质量(OR=0.49,95%CI:0.25~0.97)的人群患HUA的风险较低;高血压Ⅰ级(OR=1.24,95%CI:1.08~1.41)、Ⅱ级(OR=1.23,95%CI:1.05~1.44)、Ⅲ级(OR=1.79,95%CI:1.44~2.24)、超重(OR=1.42,95%CI:1.24~1.63)、肥胖(OR=1.85,95%CI:1.53~2.23)、中心性肥胖(OR=1.40,95%CI:1.22~1.60)、危险饮酒(OR=1.31,95%CI:1.03~1.68)和有害饮酒(OR=1.24,95%CI:1.01~1.52)、血脂异常(OR=2.03,95%CI:1.81~2.26)的人群患HUA的风险较高。结论湖北省相较于全国HUA患病率水平较低,应重点加强对危险饮酒和有害饮酒、高血压、肥胖、血脂异常人群的干预,进而降低患HUA的风险。 Objective To investigate the prevalence of hyperuricemia in adults and risk factors in Hubei province and provide evidence for the targeted interventions for the affected population.Methods The data of the study subjects,such as age,gender,education level,smoking status,alcohol consumption,physical activity,blood sugar,blood pressure,blood lipids,blood uric acid,height,weight,waist circumference,were collected from the baseline survey of the'Hubei Chronic Disease and Risk Factor Survey Project in 2020'.The risk factors for hyperuricemia were analyzed withχ^(2) test and multivariate Logistic regression models.Results According to the survey results,the crude prevalence rate of hyperuricemia was 9.36%in 19208 local residents aged>18 years.However,after weighted adjustments,the prevalence rate increased to 11.10%.The prevalence rate was positively correlated with age(trendχ^(2)=10.788,P<0.001),and the crude prevalence rate in men(19.05%)was higher than that in women(3.04%).Additionally,there was no significant difference in the prevalence rate between urban area and rural area(χ²=0.822,P>0.050).Unconditional multivariate Logistic regression analysis revealed that age,gender,hyp5ertension,body mass index,central obesity,hazardous drinking,harmful drinking and dyslipidemia were significantly associated with the risk for hyperuricemia.Age 45-59 years old[odds ratio(OR)=0.75,95%confidence interval(CI):0.65–0.86],being women(OR=0.13,95%CI:0.12–0.15),and underweight(OR=0.49,95%CI:0.25–0.97)were found to be protective factors for hyperuricemia.On the other hand,hypertension gradeⅠ(OR=1.24,95%CI:1.08–1.41),gradeⅡ(OR=1.23,95%CI:1.05–1.44),gradeⅢ(OR=1.79,95%CI:1.44–2.24),overweight(OR=1.42,95%CI:1.24–1.63),obesity(OR=1.85,95%CI:1.53–2.23),central obesity(OR=1.40,95%CI:1.22–1.60),hazardous drinking(OR=1.31,95%CI:1.029–1.679),harmful drinking(OR=1.24,95%CI:1.01–1.52),and dyslipidemia(OR=2.03,95%CI:1.81–2.26)were identified as risk factors for hyperuricemia.Conclusion It is necessary to strengthen the intervention in individuals with dangerous and harmful drinking habits,hypertension,obesity,and dyslipidemia to effectively reduce the risk for hyperuricemia.
作者 万迎超 祝淑珍 何田静 汪立先 涂画 Wan Yingchao;Zhu Shuzhen;He Tianjing;Wang Lixian;Tu Hua(Xiaonan District Center for Disease Control and Prevention,Xiaogan 432100,Hubei,China;Hubei Provincial Center for Disease Control and Prevention,Wuhan 430079,Hubei,China;Hubei Frontline Field Epidemiology Training Program,Wuhan 430079,Hubei,China)
出处 《疾病监测》 CAS CSCD 北大核心 2024年第7期895-901,共7页 Disease Surveillance
基金 中央转移支付重大公共卫生项目:湖北省卫生健康委面上项目(No.WJ2021M207)。
关键词 成年人 高尿酸血症 监测分析 Adult Hyperuricemia Surveillance and analysis
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