上海市女性常用驻留类化妆品使用状况及部分关键暴露参数分析

Analysis of the usage status and key exposure parameters of common residual cosmetics among women in Shanghai

目的调查上海市女性对常用驻留类化妆品的使用情况和使用习惯,为化妆全品安全评估工作提供每次使用量、每日使用量等关键暴露参数。方法2021年8—12月,抽取上海市女性化妆品消费者进行问卷调查,记录14 d调查期内护肤水、精华液、护肤乳、面霜、眼霜、防晒霜等6个品类的使用情况,并使用差量法计算使用的总重量。结果本研究共纳入309份有效样本量。各品类产品平均每日和每次使用量第90百分位数(P90)分别为:护肤水2.47 g和1.61 g、精华液0.84 g和0.69 g、乳液1.57 g和1.03 g、面霜0.89 g和0.80 g、眼霜0.23 g和0.21 g、防晒霜0.68 g和0.97 g。不同品类产品平均每日使用次数差异有统计学意义(H=237.42,P<0.05)。年龄≥45岁者较<45岁者护肤水的平均每日使用次数更高,差异有统计学意义(Z=3.29,P<0.05)、精华的平均每日使用量更高,差异有统计学意义(Z=2.99,P<0.05),且精华平均每日使用次数也更高,差异有统计学意义(Z=3.55,P<0.05)。结论上海市女性化妆品每次使用量、每日使用量等参数与国外人群不同,为保证化妆品安全评估的准确性,建议参考本土人群的暴露数据。

Objective To investigate the usage and habits of common residual cosmetics among women in Shanghai and to provide key exposure parameters such as per-use amount and daily usage amount for the safety assessment of cosmetics in China.Methods From August to December 2021,female cosmetic consumers in Shanghai were selected to conduct a questionnaire survey.Then,the usage of 6 types of products,including toner,essence,lotion,moisturizer,eye cream,and sunscreen,was recorded during the 14-day survey period.The total use of different products was obtained by differential weighing.Results A total of 309 samples were included in this study.The 9Oth percentile(Pgo)of the average amount applied per day and per application of each product were 2.47 g and 1.61 g for toner,0.84 g and 0.69 g for essence,1.57 g and 1.03 g for lotion,0.89 g and 0.80 g for moisturizer,0.23 g and 0.21 g for eye cream,0.68 g and 0.97 g for sunscreen.Among the survey objects,the average daily usage frequency of different categories of products had statistical significance(H=237.42,P<0.05).The average number of uses of toner was higher in those aged 45 years old or above compared with those aged<45 years old(Z=3.29,P<0.05),and the former also had a higher average amount of essence applied per day(Z=2.99,P<0.05),and a higher daily usage frequency of essence(Z=3.55,P<0.05).Conclusions The per-use and daily usage amount of cosmetics among women in Shanghai differ from those of foreign populations.It is recommended to refer to exposure data from the local population to improve the accuracy of cosmetic safety assessment.