间质性肺疾病与睡眠呼吸障碍

Interstitial lung disease and sleep-related breathing disorders

间质性肺疾病(interstitial lung disease,ILD)是一组弥漫性累及肺间质的异质性疾病群,它与睡眠呼吸障碍密切相关。作为睡眠呼吸障碍的代表性疾病,阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)是ILD的常见合并症,它可促进早期ILD发生、病程进展并导致最终的不良结局。因此,需要早期识别ILD合并的OSA,但临床缺乏强有力的筛查工具。一旦ILD合并中重度OSA,持续气道正压通气是首选治疗方法。

Interstitial lung disease(ILD)is a group of heterogeneous diseases that diffusely affects the lung mesenchyme,and is closely related to sleep-related breathing disorders. Obstructive sleep apnea(OSA),as a typical sleep-related breathing disorder,is a common complication of ILD,which can promote early ILD occurrence,disease progression,and lead to ultimate adverse outcomes. Therefore,early identification of OSA in ILD is necessary,but there is a lack of powerful screening tools in clinical practice. Once ILD is combined with moderate to severe OSA,continuous positive airway pressure ventilation is the first choice of treatment.