归芪活络口服液治疗气滞血瘀证神经根型颈椎病临床疗效观察

Clinical Observation on the Effect of Guiqi Huoluo Oral Liquid in the Treatment of Neural Root Cervical Spondylosis with Qi Stasis and Blood Stasis

目的:探讨归芪活络口服液治疗气滞血瘀证神经根型颈椎病的临床疗效。方法:选取安徽中医药大学附属太和中医院骨伤科2021年10月—2022年9月病房和门诊典型病例患者,共计60例气滞血瘀证神经根型颈椎病患者,通过SPSS 26.0软件生成随机数的方式进行随机分组,对照组30例,观察组30例。对照组接受基础治疗和西医药物治疗;观察组在基础治疗上给予归芪活络口服液进行治疗,每组疗程4周。比较2组治疗前、治疗后的疼痛视觉模拟评分(VAS)、颈椎功能障碍指数(NDI)及血清C反应蛋白(CRP)的水平变化,评估2组治疗效果。结果:经治疗后,2组的VAS和NDI评分均有所改善,但观察组的评分显著低于对照组;CRP水平在2组治疗后均有改善,但观察组的改善程度明显高于对照组;观察组的有效率为93.3%,对照组为73.3%,观察组的临床疗效明显高于对照组,差异均有统计学意义。结论:归芪活络口服液能有效治疗气滞血瘀证神经根型颈椎病,减轻疼痛和颈椎活动功能障碍,降低炎症因子的表达。其临床效果优于基础西医药物治疗。

Objective:To explore the clinical efficacy of Guiqi Huoluo oral liquid in the treatment of cervical spondy-lotic radiculopathy with Qi stagnation and blood stasis syndrome.Methods:A total of 60 patients with cervical spondy-lotic radiculopathy with qi stagnation and blood stasis syndrome were selected from the ward and outpatient department of orthopedics of Taihe Hospital of Traditional Chinese Medicine Affiliated to Anhui University of Traditional Chinese Medicine from October 2021 to September 2022.The patients were randomly divided into 2 groups by generating random numbers using SPSS 26.0 software,with 30 cases in each group.The control group received basic treatment and western medicine treatment;the observation group was given Guiqi Huoluo oral liquid in addition to basic treatment,and each group had a course of treatment of 4 weeks.The changes in the visual analogue scale(VAS)of pain,cervical dysfunction index(NDI)and serum C-reactive protein(CRP)levels before and after treatment were compared between the two groups to evaluate the therapeutic effects of the two groups.Results:After treatment,the VAS and NDI scores of both groups improved,but the scores of the observation group were significantly lower than those of the control group;the CRP levels of both groups improved after treatment,but the improvement of the observation group was significantly higher than that of the control group;the effective rate of the observation group was 93.3%,and that of the control group was 73.3%.The clinical efficacy of the observation group was significantly higher than that of the control group,and the differences were statistically significant.Conclusion:Guiqi Huoluo oral liquid can effectively treat cervical spondylotic radiculopathy with Qi stagnation and blood stasis syndrome,relieve pain and cervical vertebral activity dysfunction,and reduce the expres-sion of inflammatory factors.Its clinical effect is better than that of basic western medicine.