双氯芬酸钠胶囊致军事飞行员急性肾损伤1例

One case of acute kidney injury caused by diclofenac sodium capsules in military pilots

报道1例军事飞行员服用正常剂量双氯芬酸钠双释放肠溶胶囊2 d后发生急性肾损伤。化验血清肌酐519.1μmol/L,血尿素15.01mmol/L,血尿酸590.4μmol/L,予地塞米松注射液静脉滴注等治疗,8d后肾功能恢复正常。经1个月地面观察,患者一般情况良好,复查腹部超声、肾血管超声、血尿常规、肾功能均正常,经特勤科健康鉴定委员会讨论决定,航空医学鉴定结论:飞行合格。本文表明军事飞行员因病情需要服用双氯芬酸钠双释放肠溶胶囊前应仔细阅读药品说明书,用药后密切关注肾功能情况,切实做到保障用药安全的同时维护部队战斗力的稳定。

A case of acute kidney injury in a military pilot after taking normal dose of diclofenac sodium capsules for 2 days was reported.Serum creatinine 519.1μmol/L,blood urea 15.01 mmol/L,blood uric acid 590.4μmol/L were tested,and dexamethasone injection was given intravenously.After 8 days,renal function returned to normal.After 1 month of ground observation,the patient was generally in good condition,and the abdominal ultrasound,renal vascular ultrasound,hematuria routine,and renal function were all normal.After discussion and decision by the Special Service Health Identification Committee,the aviation medical identification conclusion was that the flight was qualified.This article shows that military pilots should carefully read the drug instructions before taking diclofenac sodium capsules due to their illness,pay close attention to renal function after medication,and effectively ensure the safety of medication while maintaining the stability of the combat effectiveness of the troops.