CT联合CEA在肺磨玻璃样结节诊断的价值

Value of CT combined with CEA in the diagnosis of ground-glass nodules of the lung

目的探讨CT联合癌胚抗原(carcinoembryonic antigen,CEA)诊断肺磨玻璃样结节患者的临床效果。方法选取确诊为肺磨玻璃样结节的120例患者,均接受CT和CEA检查,以术后病理结果为金标准,将其分为良性组(51例)和恶性组(69例),比较两组的CT影像学特征与CEA水平。结果恶性组患者病灶表现为边胸膜凹陷征、毛刺征、空泡征和边缘分叶征的病例数明显多于良性组,且两组差异均具有统计学意义(P<0.05)。恶性组患者的CEA水平为(15.05±3.78)ng/mL,明显高于良性组患者的CEA水平(8.21±2.53)ng/mL,且两组差异具有统计学意义(P<0.05)。CT联合CEA诊断恶性结节的敏感度可达94.20%。结论在肺磨玻璃样结节的诊断中,CT和CEA联合诊断具有较高的灵敏度和特异度,对肺磨玻璃样结节的良恶性诊断具有重要的临床价值。

Objective To explore the efficacy of CT combined with carcinoembryonic antigen(CEA)in the diagnosis of pulmonary ground-glassy nodules.Methods A total of 120 patients diagnosed with pulmonary ground glass nodules were selected,all the patients were received CT and CEA examinations.The patients were divided into benign group(51 cases)and malignant group(69 cases)according to postoperative pathological results,and the CT imaging features and CEA levels were compared between the two groups.Results The number of cases with side pleural depression sign,burr sign,vacuole sign and edge lobed sign in the evil group was significantly higher than that in the benign group,and the difference between the two groups was statistically significant(P<0.05).The CEA level of malignant group was(15.05±3.78)ng/mL,which was significantly higher than that of benign group(8.21±2.53)ng/mL,and the difference between the two groups was statistically significant(P<0.05).The sensitivity of CT combined with CEA in the diagnosis of malignant nodules could reach 94.20%.Conclusion The combined diagnosis of CT and CEA has high sensitivity and specificity in the diagnosis of pulmonary ground-glass nodules,which has important clinical value in the diagnosis of benign and malignant pulmonary ground-glass nodules.