环境介质中防晒剂的残留与毒性研究进展

Research Progress on Residues and Toxicity of Sunscreens in Environmental Media

紫外线辐射可引起短期皮肤晒伤、长期皮肤红斑和色素沉着等健康问题,甚至导致皮肤癌等严重病变。为减弱紫外线辐射造成的伤害,防晒剂被添加进各种产品中。综述了近10年来紫外防晒剂在水环境(<LOD~6969 ng/L)、沉积物(<LOD~126.5 ng/g)、水生生物(LOD~11875 ng/g)、普通人群(<LOD~525 ng/mL)、室内灰尘(66.6~60600 ng/g)等环境介质中的暴露水平研究结果,讨论了环境中防晒剂的毒性效应,包括遗传毒性、生殖发育毒性、内分泌干扰毒性、联合暴露毒性以及降解产物毒性,并展望了该领域未来的研究方向,以期为防晒剂的安全使用和科学管控提供参考。

UV radiation can cause health problems such as short-term sunburn,long-term skin erythema and hyperpigmentation,and even lead to serious lesions such as skin cancer.To attenuate the damage caused by UV radiation,sunscreens are added to various products.The exposure levels of UV sunscreens in environmental media such as aqueous environments(<LOD-6969 ng/L),sediments(<LOD-126.5 ng/g),aquatic organisms(LOD-11875 ng/g),the general population(<LOD-525 ng/mL),and indoor dust(66.6-60600 ng/g)in the last 10 years were reviewed in this paper,and the toxic effects of sunscreens in the environment were discussed,including genotoxicity,reproductive developmental toxicity,endocrine disrupting effect,combined exposure toxicity and degradation product toxicity,and the future research directions in this field were envisioned,with a view to providing references for the safe use of sunscreens and the scientific control of sunscreens.