基于TOUS的儿童癌症相关认知障碍影响因素的研究进展

Research progress in influencing factors of cancer-related cognitive impairment in children based on theory of unpleasant symptoms

不同类型肿瘤或常见的抗肿瘤治疗措施可导致患儿出现癌症相关认知障碍(CRCI)。依据不愉快症状理论(TOUS),该文总结了3个层面共计20个关键影响因素:生理层面包括疾病类型、治疗方式、治疗相关并发症、年龄、性别等;心理层面涵盖疲乏、焦虑、抑郁及睡眠障碍等;背景层面涉及家庭环境与社会经济地位、父母受教育程度及体育运动等,并对这些影响因素进行了阐述,旨在为该领域的进一步研究提供参考。

Different types of tumors or common anti-tumor treatment measures can lead to cancer-related cognitive impairment(CRCI)appearance in pediatric patients.Based on the theory of unpleasant symptoms(TOUS),this paper summarizes a total of 20 key influencing factors in 3 levels:the physiological level includes the disease type,treatment method,treatment-related complications,age,gender,etc.;the psychological level encompasses fatigue,anxiety,depression,and sleep disturbances,etc.;the background level involves the family environment and socioeconomic status,parental education level,physical activity,etc.This paper elucidates these influencing factors to provide reference for further research in this field.