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牛体外胚胎生产过程中培养液添加物研究进展

Research Progress on Culture Medium Additives in Bovine In Vitro Embryo Production
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摘要 牛体外胚胎生产是一种广泛应用于畜牧生产和生物研究的现代繁殖技术,在促进肉牛和奶牛品种改良以及高效繁育中发挥着关键作用。随着分子生物学、生物化学和细胞生物学技术的不断发展,牛体外胚胎生产技术已取得了长足进步。然而,当前牛体外胚胎生产技术仍存在胚胎生产效率低和胚胎发育潜能差等瓶颈问题,在很大程度上限制了该技术的规模化推广应用。本文系统综述了牛体外胚胎生产中经典添加物和最新添加物的研究进展,旨在为优化构建不同添加物组合的技术体系提供参考,以期更加高效地获得牛体外优质胚胎。 Bovine embryo in vitro production(IVP)is a modern reproductive biotechnology,which is widely used in livestock production and biological research and plays an essential role in promoting breed improvement and reproductive efficiency for both beef and dairy cattle.As development of molecular biology,biochemistry and cell biology,a great progress has been made in bovine IVP.However,the current bovine IVP is still facing bottleneck problems,such as low efficiency of in intro embryo production and poor embryonic development potential,seriously hindering the further large-scale promotion and application of this technology.In this paper,the research progress of classical and latest additives in bovine IVP was systematically reviewed,intending to provide references for optimizing and constructing the technical system of different additive combinations,and aiming to more efficiently obtain high-quality bovine in vitro embryos.
作者 戴舒颖 刘青 李爱国 余博 陈洪波 DAI Shuying;LIU Qing;LI Aiguo;YU Bo;CHEN Hongbo(Laboratory of Genetic Breeding,Reproduction and Precision Livestock Farming,School of Animal Science and Nutritional Engineering,Wuhan Polytechnic University,Wuhan 430023,China;Shiyan Centers for Disease Control and Prevention,Shiyan 442099,China)
出处 《畜牧兽医学报》 CAS CSCD 北大核心 2024年第8期3309-3320,共12页 ACTA VETERINARIA ET ZOOTECHNICA SINICA
基金 湖北省重点研发计划项目(2022BBA007) 湖北省重点研发专项(2023BBB056) 武汉轻工大学引进(培养)人才科研启动项目(2023R2010)。
关键词 胚胎 培养液 受精 添加物 bovine embryo culture solution fertilization additive
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