鼻腔呼吸道上皮腺瘤样错构瘤临床特点分析

Clinical characteristics analysis of respiratory epithelial adenomatoid hamartoma in the nasal cavity

目的对12例鼻腔呼吸道上皮腺瘤样错构瘤(REAH)的临床特点进行分析总结。方法对2018年11月-2022年12月聊城市第二人民医院耳鼻咽喉科治疗的12例鼻腔REAH患者进行回顾性研究。12例患者中,男9例,女3例;平均年龄53.16岁。对其好发部位、主要症状体征、影像学特征、手术方法进行分析。结果所有患者随访4年以上,11例未再复发,1例复发。病理改变以被间质组织分隔的广泛增生的圆形或椭圆形腺体结构为主。结论鼻腔REAH好发部位为嗅裂区,临床症状缺乏特异性,病理学诊断是金标准,手术彻底切除病变是有效的治疗手段。

Objective To analyze and summarize the clinical characteristics of 12 cases of nasal respiratory epithelial adenomatoid hamartoma(REAH).Methods A retrospective study was conducted on 12 patients with nasal REAH treated in the Department of Otolaryngology,Liaocheng Second People’s Hospital from November 2018 to December 2022.The 12 patients(9 males and 3 females)had an average age of 53.16 years.The predilection sites,main symptoms and signs,imaging features and surgical methods were analyzed.Results Following up for more than 4 years,11 cases have not recurred and 1 case has recurred.The pathological changes are mainly round or elliptical glandular structures with extensive proliferation separated by interstitial tissue.Conclusions The most common site of nasal REAH is the olfactory cleft area.The clinical symptoms lack specificity.Pathological diagnosis is the gold standard,and complete surgical removal of the lesion is an effective treatment.