摘要
自主神经失衡被认为在心律失常等心血管疾病的病理生理机制中至关重要,针对自主神经调控心血管疾病已成为一个研究热点。随着材料科学、医学、物理学为代表的多学科快速发展和交叉融合,近几十年来神经调控领域取得了重大进展,针对自主神经调控心血管疾病已开发了许多新的干预策略。现重点综述心脏自主神经调控领域中交叉策略研究新进展,以及目前技术的不足和改进方向,指导自主神经调控治疗心血管疾病取得进一步转化应用。
Autonomic imbalance is thought to be crucial in the pathophysiological mechanisms of cardiovascular diseases such as arrhythmias.Autonomic modulation of cardiovascular diseases has become a research hotspot.With the rapid development and intersection of multiple disciplines,such as materials science,medicine,and physics,the field of neuromodulation has made significant progress in recent decades.Many new intervention strategies have been developed for autonomic neuromodulation of cardiovascular diseases.We now focus on reviewing the new advances in cross-cutting strategies in the field of cardiac autonomic neuromodulation,as well as the shortcomings and directions for improvement of the current technology,to guide the autonomic neuromodulation therapy for cardiovascular diseases to achieve further translational applications.
作者
刘承哲
江洪
余锂镭
LIU Chengzhe;JIANG Hong;YU Lilei(Department of Cardiology,Cardiovascular Hospital,Renmin Hospital of Wuhan University,Cardiac Autonomic Nervous Research Center,Cardiovascular Research Institute,Wuhan University,Hubei Key Laboratory of Cardiology,Wuhan 430060,Hubei,China)
出处
《心血管病学进展》
CAS
2024年第8期742-746,共5页
Advances in Cardiovascular Diseases
基金
国家自然科学基金面上项目(82270532,82370286)
国家自然科学基金专项项目(82241057)
湖北省自然科学基金创新群体项目(2021CFA010)。
关键词
心脏自主神经
神经调控
医工交叉
功能性纳米材料
Cardiac autonomic nerve
Neuromodulation
Medicine-engineering interdisciplinary
Functional nanomaterials