血清睾酮和中性粒细胞与淋巴细胞计数比值在良性前列腺增生筛查中的临床价值

Clinical value of serum testosterone and neutrophil to lymphocyte ratio in screening for benign prostatic hyperplasia

目的:探讨血清睾酮(Testosterone,T)和中性粒细胞与淋巴细胞计数比值(Neutrophil to lymphocyte ratio,NLR)在良性前列腺增生(Benign prostatic hyperplasia,BPH)筛查中的临床价值。方法:选取2023年2月至2024年2月于我院确诊的30例BPH患者为观察组,另选取2023年2月至2024年2月于本院体检的健康男性30例为对照组。采集两组受试者血液样本,检测血清T水平和NLR,并进行对比分析;并采用ROC曲线分析血清T和NLR水平对BPH的诊断价值。结果:观察组血清T与NLR水平均高于对照组(P<0.05)。经Logistic回归分析显示,血清T和NLR与BPH有关(P<0.05)。经ROC曲线分析显示,血清T和NLR均对BPH有较好的诊断价值,且联合检测诊断BPH的AUC高于各项单独检测(P<0.05)。结论:血清T与NLR均对BPH有一定的诊断价值,且联合检测的诊断价值较高,可作为临床辅助BPH的筛查指标。

Objective:To explore the clinical value of serum testosterone(T)and neutrophil to lymphocyte ratio(NLR)in screening for benign prostatic hyperplasia(BPH).Methods:30 BPH patients diagnosed in our hospital from February 2023 to February 2024 were selected as the observation group,and another 30 healthy males who underwent physical examinations in our hospital from February 2023 to February 2024 were selected as the control group.Collect blood samples from two groups,detect serum T levels and NLR,and conduct comparative analysis;And ROC curves were used to analyze the diagnostic value of serum T and NLR levels for BPH.Results:The serum T and NLR levels in the observation group were higher than those in the control group(P<0.05).Logistic regression analysis showed that serum T and NLR were associated with BPH(P<0.05).According to ROC curve analysis,both serum T and NLR have good diagnostic value for BPH,and the AUC of combined detection for diagnosing BPH is higher than that of individual tests(P<0.05).Conclusion:Both serum T and NLR have certain diagnostic value for BPH,and the combined detection has high diagnostic value,which can be used as a clinical auxiliary screening indicator for BPH.