右心声学造影与增强经颅多普勒检查诊断卵圆孔未闭右向左分流的价值分析

Value of Agitated saline contrast echocardiography and enhanced transcranial Doppler in diagnosis of right-to-left shunt of patent foramen ovale

目的:观察右心声学造影联合增强经颅多普勒在卵圆孔未闭右向左分流(Patent foramen ovale-Right-to-left shunt,PFO-RLS)诊断中的应用价值。方法:选取本院2020年4月至2021年4月期间诊治的60例疑似PFO-RLS患者作为研究对象。研究对象分别接受经食管超声心动图、右心声学造影和增强经颅多普勒检查,记录检查结果。将经食管超声心动图检查结果作为PFO-RLS诊断金标准,明确右心声学造影和增强经颅多普勒单独及联合诊断PFO-RLS的价值。结果:经食管超声心动图诊断出PFO阳性52例,PFO-RLS阳性40例;行一致性检验,右心声学造影、增强经颅多普勒分别诊断PFO、PFO-RLS与金标准的一致性均一般,二者联合诊断PFO、PFO-RLS与金标准的一致性K值均>0.80,一致性较好。结论:右心声学造影联合增强经颅多普勒用于PFO-RLS的诊断,与金标准有较好的一致性。

Objective:To observe the application value of agitated saline contrast echocardiography combined with enhanced transcranial Doppler in the diagnosis of right-to-left shunt of patent foramina ovale(PFO-RLS).Methods:60 suspected PFO-RLS patients diagnosed and treated in our hospital from April 2020 to April 2021 were selected as the study objects.Subjects underwent transesophageal echocardiography,agitated saline contrast echocardiography and enhanced transcranial Doppler.Using the results of transesophageal echocardiography as the gold standard in the diagnosis of PFO-RLS,the value of agitated saline contrast echocardiography and enhanced transcranial Doppler alone and combined in the diagnosis of PFO-RLS was determined.Results:Transesophageal echocardiography diagnosed PFO positive in 52 cases and PFO-RLS positive in 40 cases.Consistency test was performed.The consistency of agitated saline contrast echocardiography,enhanced transcranial Doppler and gold standard in the diagnosis of PFO,PFO-RLS was general,and the consistency of K value of the combined diagnosis and gold standard of PFO,PFO-RLS was greater than 0.80,indicating a good consistency.Conclusion:agitated saline contrast echocardiography combined with enhanced transcranial Doppler in the diagnosis of PFO-RLS is in good agreement with the gold standard.