针刺内关穴对心房颤动节律控制的作用机制研究进展

Research progress on mechanisms of acupuncture at Neiguan point(PC6)for rhythm control of atrial fibrillation

心房颤动(简称“房颤”)是一种常见的心律失常疾病,其治疗以节律控制为关键目标。针刺内关穴能够使房颤转复窦性心律、缩短房颤持续时间、缓解临床症状,对房颤治疗具有多方面的积极作用;其机制可能与良性调节心脏自主神经、双向调节心率、改善心肌结构重构及电生理重构等作用有关。通过对针刺内关穴治疗房颤的相关临床与机制研究进行评述,为针刺内关穴对房颤节律控制的有效性提供依据,并为未来的相关研究方向提供思路。

Atrial fibrillation(AF)is a common arrhythmia disease,and its treatment focuses on rhythm control as a key goal.Acupuncture at Neiguan point(PC6)can convert AF into sinus rhythm,shorten the duration of AF,alleviate clinical symptoms,and has a positive effect on the treatment of AF in various aspects.Its mechanisms may be related to benign regulation of cardiac autonomic nervous system,bidirectional regulation of heart rate,improvement of myocardial structural remodeling and electrophysiological remodeling.This paper reviews the clinical and mechanistic researches on the treatment of AF with acupuncture at Neiguan point(PC6),in order to provide a basis for the effectiveness of acupuncture at Neiguan point(PC6)on AF rhythm control,and to provide ideas for future related research directions.