广西百色市城区体检人群胆囊结石检出率及影响因素研究

Detection rate and influencing factors of gallstones in the physical examination population of urban Baise City,Guangxi

目的调查广西百色市城区体检人群胆囊结石的检出率及影响因素。方法采用便利抽样法,对2020年11月至2021年6月期间在广西百色市城区三家医院参加健康体检的5294名体检者的资料进行回顾性横断面分析,收集其人口学、影像学(腹部B超)及实验室检查等资料,统计分析其胆囊结石的检出率,比较胆囊结石和非胆囊结石组相关血生化指标的差异,并通过二元Logistic回归模型,分析影响研究对象胆囊结石发生的因素。结果本次调查共检出胆囊结石391人,检出率为7.39%。多因素Logistic回归分析发现:年龄(OR=1.028,P<0.001)、BMI(OR=1.480,P<0.001)、ALP(OR=1.005,P=0.022)、TG(OR=0.901,P=0.006)、HDL-C(OR=0.635,P=0.014)、SBP(OR=1.026,P<0.001)、合并脂肪肝(OR=1.301,P=0.040)是胆囊结石的独立影响因素。结论广西百色市城区体检人群胆囊结石检出率较高。老年人、肥胖、肝功能异常、血脂异常、合并脂肪肝是胆囊结石发生的高危影响因素。

Objective To investigate the detection rate of gallstones and their influencing factors in the physical examination population of urban Baise city,Guangxi.Methods Using convenience sampling,we conducted a retrospective cross-sectional analysis of 5294 individuals who underwent health check-ups in three urban hospitals in Baise city,Guangxi,from November 2020 to June 2021.We collected demographic data,imaging results(abdominal ultrasound)and laboratory examination findings.The detection rate of gallstones was statistically analyzed,and relevant blood biochemical indicators were compared between groups with and without gallstones.A binary logistic regression model was used to analyze factors influencing gallstone occurrence.Results A total of 391 cases of gallstones were detected in this survey,with a detection rate of 7.39%.Multivariate logistic regression analysis identified the following independent factors influencing gallstone formation:age(OR=1.028,P<0.001),BMI(OR=1.480,P<0.001),ALP(OR=1.005,P=0.022),TG(OR=0.901,P=0.006),HDL-C(OR=0.635,P=0.014),SBP(OR=1.026,P<0.001)and comorbid fatty liver(OR=1.301,P=0.040).Conclusion The detection rate of gallstones is relatively high in the physical examination population of urban Baise City,Guangxi.Advanced age,obesity,abnormal liver function,dyslipidemia and comorbid fatty liver are the high-risk factors for gallstone formation.