当归四逆汤合抵挡汤加减对糖尿病周围神经病变患者中医证候积分的影响分析

Influence of Danggui Sini Decoction and Didang Decoction on Traditional Chinese Medicine Syndrome Score of Patients with Diabetes Peripheral Neuropathy

目的分析当归四逆汤合抵挡汤加减对糖尿病周围神经病变患者的治疗价值。方法回顾性选取2021年6月—2023年2月郧阳区中医医院收治的120例糖尿病周围神经病变患者的临床资料,以不同治疗方式分为研究组(甲钴胺片+当归四逆汤合抵挡汤加减治疗)和对照组(甲钴胺片治疗),各60例。对比两组疗效、中医证候积分(肢体麻木不仁、肢末冷痛、倦怠乏力、气短懒言、腰膝酸软、四肢发凉)和多伦多临床评分系统评分及运动神经(腓总神经、正中神经、胫神经)传导速度。结果研究组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。研究组的腓总、正中及胫神经运动传导速度均明显高于对照组,差异有统计学意义(P均<0.05)。研究组各项中医证候积分均低于对照组,差异有统计学意义(P均<0.05)。研究组的多伦多临床评分系统得分明显低于对照组,差异有统计学意义(P<0.05)。结论当归四逆汤合抵挡汤加减治疗,可减轻糖尿病周围神经病变患者症状负担,提高临床疗效,改善病情。

Objective To analyze the therapeutic value of Danggui Sini Decoction combined with Didang Decoction in diabetic peripheral neuropathy patients.Methods Clinical data of 120 patients with diabetic peripheral neuropathy treated in Yunyang District Hospital of Traditional Chinese Medicine from June 2021 to February 2023 were retrospec-tively selected,and were divided into study group(methylcobalamin tablet+Danggui Sini Decoction combined with Huifu decoction treatment)and control group(methylcobalamin tablet treatment),with 60 cases each.The efficacy,Traditional Chinese Medicine Syndrome Scores(numbness of the limbs,cold pain at the end of the limbs,fatigue,shortness of breath,weakness of the waist and knees,cold limbs),Toronto Clinical Scoring System Score and motor nerve(common fibular nerve,median nerve,tibial nerve)conduction velocity were compared between the two groups.Results The total treatment effective rate of the study group was higher than that of the control group,and the differ-ence was statistically significant(P<0.05).The motor conduction velocities of common fibular nerve,median nerve and tibial nerve in the study group were significantly higher than those in the control group,and the differences were statis-tically significant(all P<0.05).The Traditional Chinese Medicine Syndrome Scores of the study group were lower than those of the control group,and the differences were statistically significant(all P<0.05).The Toronto Clinical Scoring System Score of the study group was significantly lower than that of the control group,and the difference was statisti-cally significant(P<0.05).Conclusion Danggui Sini Decoction combined with Didang Decoction can reduce the symp-tom burden of diabetic peripheral neuropathy patients,improve the clinical efficacy and improve the condition.