血管源性脑白质病变的视网膜成像研究进展

Progress in Clinical Research on Retinal Imaging in Vascular White Mat⁃ter Lesions

血管源性脑白质病变(White Matter Lesions, WMLs)在老年人群中发病率高,往往引起血管性认知障碍和痴呆。视网膜血管在胚胎学起源和解剖结构上类似于脑小血管,而视网膜神经纤维层又是大脑的延伸白质。近年来越来越多的研究证实WMLs可引起视网膜改变,本综述总结了现有的研究结果,概述了WMLs患者视网膜成像临床研究现状,以期指导临床对WMLs的筛查和预防。

The incidence of vascular white matter lesions(WMLs)is high in the elderly population,which often causes vascular cognitive impairment and dementia.Retinal blood vessels are similar to brain small blood vessels in embryological origin and anatomical structure,and the retinal nerve fiber layer is the extended white matter of the brain.In recent years,a growing number of studies have substantiated that WMLs can cause retinal changes.This article reviewed the existing research results and summarizes the current clinical research status of retinal imaging in patients with WMLs,with a view to guiding clinical screening and prevention.