甘油三酯-葡萄糖指数在老年急性心肌梗死诊断中的应用价值

Application Value of Triglyceride-glucose Index in Diagnosis of Acute Myocardial Infarction in Elderly Patients

目的:分析甘油三酯-葡萄糖(TyG)指数在老年急性心肌梗死患者诊断中的应用价值。方法:选取2022年6月—2023年6月于扬州大学附属苏北人民医院经冠脉造影确诊的老年急性心肌梗死患者248例作为观察组,并根据Gensini评分分为轻中度病变组(Gensini评分≤50分)和重度病变组(Gensini评分>50分两个亚组);将同期进行体检的50名健康人作为健康组。收集其临床资料,对比观察组、健康组TyG指数,比较轻中度病变组、重度病变组临床资料,分析老年急性心肌梗死患者病变严重程度的影响因素,分析TyG指数与老年急性心肌梗死患者病变严重程度的相关性以及TyG指数评估老年急性心肌梗死患者病变严重程度的效能。结果:观察组TyG指数高于健康组,组间差异显著(P<0.05)。急性心肌梗死患者Gensini评分与TyG指数呈正相关(r=0.319,P<0.001)。TyG指数高为老年急性心肌梗死患者病变严重程度的独立危险因素(P<0.001),TyG指数评估老年急性心肌梗死患者病变严重程度的受试者操作特征曲线下面积为0.664。结论:TyG指数是急性心肌梗死患者病变严重程度的独立影响因素,可作为疾病严重程度的评估工具。

Objective:To analyze the diagnostic value of triglyceride-glucose(TyG)index in elderly patients with acute myocardial infarction.Methods:A total of two hundred and forty-eight elderly patients with acute myocardial infarction diagnosed by coronary angiography in Jiangsu North People's Hospital Affiliated to Yangzhou University from June 2022 to June 2023 were selected as the observation group.According to Gensini score,the patients were divided into mild and moderate disease group(Gensini score≤50 points)and severe disease group(Gensini score>50 points).Fifty healthy people who underwent physical examination during the same period were selected as the health group.Clinical data were collected and TyG index was compared between the observation group and the healthy group.The clinical data of mild to moderate disease group and severe disease group were compared to analyze the factors affecting the severity of disease in elderly patients with acute myocardial infarction.The correlation between TyG index and the severity of lesions in elderly patients with acute myocardial infarction,and the efficacy of TyG index in evaluating the severity of lesions in elderly patients with acute myocardial infarction were analyzed.Results:TyG index in observation group was higher than that in health group,and the difference was significant(P<0.05);Gensini score was positively correlated with TyG index in patients with acute myocardial infarction(r=0.319,P<0.001);high TyG index was an independent risk factor for the severity of disease in elderly patients with acute myocardial infarction(P<0.001);the area under the subject operation characteristic curve of TyG index to evaluate the severity of disease in elderly patients with acute myocardial infarction was 0.664.Conclusion:TyG index is an independent factor affecting the severity of acute myocardial infarction,and can be used as a tool to evaluate the severity of the disease.