改良型富血小板纤维蛋白牙槽窝保存术在牙槽骨量保护及牙槽骨形态维持中的作用研究

Study on the Role of Modified Platelet-Rich Fibrin in Socket Preservation for Preservation of Alveolar Bone Quantity and Maintenance of Alveolar Bone Morphology

目的:分析改良型富血小板纤维蛋白(PRF)牙槽窝保存术在牙槽骨量保护及牙槽骨形态维持中的作用研究。方法:根据简单随机分组法将本院2021年9月至2023年9月收治的105例接受牙槽窝保存术治疗患者分为观察组(n=52,改良型PRF治疗)和对照组(n=53,常规治疗);对比两组患者临床治疗效果,治疗前后牙槽骨量及牙槽骨形态变化。结果:与对照组比,观察组愈合时间短(P<0.05),观察组术后1周、术后2周创口愈合率均高于对照组(P<0.05)。术后4个月,两组BC1差异均无统计学意义(P>0.05),观察组平均灰度值2(BD2)及骨获得量(BG)均高于对照组(P<0.05),观察组BC2低于对照组(P<0.05)。术后6个月,观察组牙槽骨宽度、高度及骨密度水平及改善幅度均大于对照组(P<0.05)。术后3个月,观察组SBI低于对照组(P<0.05)。结论:改良型PRF用于牙槽窝保存术中可发挥较好的植骨效果,有助于创口愈合,在牙槽骨量、牙槽骨形态维持中具有较好的作用。

Objective:To analyze the role of modified platelet-rich fibrin(PRF)in socket preservation for the preservation of alveolar bone quantity and maintenance of alveolar bone morphology.Methods:A total of 105 patients undergoing socket preservation surgery from September 2021 to September 2023 were randomly divided into an observation group(n=52,treated with modified PRF)and a control group(n=53,conventional treatment).Clinical treatment outcomes,changes in alveolar bone quantity,and alveolar bone morphology before and after treatment were compared between the two groups.Results:Compared with the control group,the observation group had a shorter healing time(P<0.05),and higher wound healing rates at 1 week and 2 weeks postoperatively(P<0.05).At 4 months postoperatively,there were no significant differences in bone crest level(BC1)between the two groups(P>0.05),but the observation group had higher mean gray value(BD2)and bone gain(BG)compared to the control group(P<0.05),while BC2 was lower in the observation group(P<0.05).At 6 months postoperatively,the observation group showed greater improvements in alveolar bone width,height,density levels,and improvement rates compared to the control group(P<0.05).At 3 months postoperatively,the sulcus bleeding index(SBI)was lower in the observation group than in the control group(P<0.05).Conclusion:Modified PRF used in socket preservation surgery demonstrates good osteogenic effects,aids in wound healing,and plays a beneficial role in preserving alveolar bone quantity and maintaining alveolar bone morphology.