伤害敏感指数在疼痛管理中的研究进展

Research progress on the index of consciousness 2 in pain management

有效的围手术期疼痛管理对于加速患者康复和减少不良事件的发生至关重要,而敏感且可靠的疼痛监测在其中起到了不可或缺的作用。基于脑电图信号衍生的意识指数(index of consciousness, IoC)是一种新兴的麻醉深度监测指标,已经逐步应用于全身麻醉过程中。伤害敏感指数(IoC2)用于镇痛程度的监测,也可作为多种手术类型中的疼痛管理的监测指标评价镇痛效果,指导合理使用镇痛药物,减少围术期相关不良事件,在临床上具有良好的优势及应用前景。本文旨在综述IoC2的基本原理、临床研究现状以及优劣势等方面,并与其他镇痛监测作比较,为IoC2的临床应用提供可靠的依据。

Effective perioperative pain management is essential for accelerating recovery and minimizing adverse events,in which sensitive and reliable pain monitoring plays an indispensable role.The index of consciousness(IoC)derived from electroencephalogram signal is an emerging index for monitoring the depth of anesthesia,and has been progressively applied during general anesthesia.The IoC2,is used for the monitoring of the degree of analgesia,and can be used as a pain management monitoring index in a variety of surgical types to evaluate the analgesic effect,guiding the rational use of analgesic drugs,and reducing perioperative-related adverse events.I it has good advantages and application prospects in the clinic.The purpose of this paper is to summarize the basic principle,current status of clinical research,advantages and disadvantages of IoC2,and to make a simple comparison with other analgesic monitoring,so as to provide a reliable basis for the clinical application of IoC2.