基于数据挖掘的中医药治疗社区获得性肺炎患者的用药特点研究

Medication Characteristics of Traditional Chinese Medicine in the Treatment of Patients with Community-Acquired Pneumonia Based on Data Mining

目的:探讨中医药治疗社区获得性肺炎的用药特点。方法:根据纳入、排除标准,对2020—2023年该院社区获得性肺炎住院患者的病历资料进行整理汇总,采用数据挖掘技术对处方中的中药进行频数分析、关联规则分析和复杂网络分析。结果:共涉及71首处方,114味中药,总频次达902次。中药的四气中,寒、平性频次最高;五味中,苦、甘、辛味频次最高;归经中,肺、胃、脾经频次最高。中药种类中,化痰止咳平喘药、清热药、补虚药和解表药频次最高。药物组合关联规则显示,紫菀-白前、芦根-桃仁、紫菀-款冬花、连翘-金银花、芦根-玄参和芦根-淡竹叶为常用药对。提炼出1个核心处方,为苦杏仁、浙贝母、桔梗、枇杷叶、芦根、紫菀、黄芩及甘草。结论:初步掌握了中医药治疗社区获得性肺炎的用药特点,为临床辨证论治社区获得性肺炎提供了一定的参考依据。

OBJECTIVE:To probe into the medication characteristics of traditional Chinese medicine in the treatment of community-acquired pneumonia.METHODS:According to the inclusion and exclusion criteria,the medical records of inpatients with community-acquired pneumonia from 2020 to 2023 were compiled and summarized,the frequency analysis,association rule analysis and complex network analysis on traditional Chinese medicines in the prescriptions were performed by data mining techniques.RESULTS:There were 71 prescriptions and 114 flavors of traditional Chinese medicine included in the study,with a total frequency of 902 times.Among the four Qi,coldness and flatness had the highest frequency,among the five flavors,bitterness,sweetness and pungency had the highest frequency,among the channel tropism,lung,stomach and spleen channels had the highest frequency.Among the drug categories,the phlegm-reducing,cough-relieving and asthma-relieving drugs,heat-clearing drugs,deficiency tonic drugs and antidepressant drugs took the lead.The drug combination association rules showed that Asteris radix et rhizoma-Cynanchistauntonii rhizoma et radix,Phragmitis rhizoma-Persicae semen,Asteris radix et rhizoma-Farfarae flos,Forsythiae fructus-Lonicerae japonicae flos,Phragmitis rhizoma-Figwort root,Phragmitis rhizom a-lophatherum gracile were the commonly used traditional Chinese medocone.One core prescription extracted was Amygdalus communis vas,Fritillariae Thunbrgii Bulbus,Platycodon Grandiforus,Eriobotryae Folium,Phragmitis rhizom a,Asteris radix et rhizoma,Scutellariae Radix and licorice.CONCLUSIONS:Preliminary understanding for medication characteristics of traditional Chinese medicine in the treatment of community-acquired pneumonia provides a certain reference basis for clinical identification and treatment of community-acquired pneumonia.