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鱼腥草的研究进展及其质量标志物的预测分析

Research Progress on Houttuynia cordata and Predictive Analysis of Its Quality Markers
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摘要 鱼腥草为我国传统的药食同源中药材之一,其化学成分类型丰富,包含挥发油类、黄酮类、生物碱类、苯丙素类、甾体类等。研究表明,鱼腥草具有抗炎、抗肿瘤、抗菌和抗病毒等药理作用。该文综述了鱼腥草的本草考证、化学成分及药理作用,并根据中药质量标志物(quality marker,Q-Marker)的概念,从植物亲缘学、传统药性及药效、不同产地和采收时期、可入血成分和化学成分可测性等方面对鱼腥草的质量标志物进行预测分析,以期为鱼腥草的质量控制研究提供参考。 Houttuynia cordata,which can be taken as a food and medicine,is one of the traditional Chinese herbs in China.Houttuynia cordata is rich in chemical components like volatile oils,flavonoids,alkaloids,phenylpropanoids,and steroids etc.Modern studies have shown that Houttuynia cordata has anti-inflammatory,antitumor,antibacterial,antiviral,and other pharmacological effects.In this paper,herbal textual research,chemical composition and pharmacological effects of Houttuynia cordata were integrated and summarized.The quality markers of Houttuynia cordata were predicted and analyzed according to the concept of quality markers of traditional Chinese medicine in terms of phytopharmacology,medicinal properties and medicinal efficacy,different production areas and harvesting period,constituents absorbed in the blood and chemical components measurability.The aim is to provide references for the quality control study of Houttuynia cordata.
作者 王连睿 东红阳 苗明三 WANG Lianrui;DONG Hongyang;MIAO Mingsan(School of Pharmacy,Henan University of Chinese Medicine,Zhengzhou 450046 Henan,China)
出处 《中药新药与临床药理》 CAS CSCD 北大核心 2024年第7期1084-1092,共9页 Traditional Chinese Drug Research and Clinical Pharmacology
基金 国家自然科学基金项目(82274119) 河南省重大科技专项(221100310400) 岐黄学者项目(国中医药人教函2022-6)。
关键词 鱼腥草 质量标志物 本草考证 化学成分 药理作用 Houttuynia cordata quality markers herbal textual research chemical constituents pharmacological effects
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