摘要
连翘为临床常用的清热解毒类中药,主要含有苯乙醇苷类、木脂素类、萜类及挥发油、黄酮类等化学成分。大量研究证实连翘具有抗炎、抗菌、抗病毒、抗癌等多种药理作用,且安全性较高。该文系统综述了连翘的化学成分、药理作用及安全性的研究进展,以总结连翘的相关研究成果,并为其进一步的开发研究和临床应用提供思路。
Forsythiae fructus,a traditional Chinese medicine for heat clearing and detoxifying,is commonly used in clinic.It mainly contains phenylethanol glycosides,lignans,terpenoids,volatile oils,flavonoids and other chemical components.Numerous studies have confirmed that forsythiae fructus has anti-inflammatory,antibacterial,antiviral,anti-cancer and other pharmacological effects.Moreover,it has high safety.In this paper,the chemical composition,pharmacological action and safety of forsythiae fructus were reviewed.The aim of this study is to collect the relevant research achievements of forsythiae fructus,and to provide ideas and references for its further research and clinical application.
作者
马雪百合
郭健敏
温玉莹
代彩玲
杨威
MA Xuebaihe;GUO Jianmin;WEN Yuying;DAI Cailing;YANG Wei(Guangdong Lewwin Pharmaceutical Research Institute Co.,Ltd.,Guangzhou Bay Area Institute of Biomedicine,Guangdong Provincial Key Laboratory of Drug Non-clinical Evaluation and Research,TCM Non-clinic Evaluation Branch of National Engineering Research Center for Modernization of Traditional Chinese Medicine,Guangdong Engineering Research Center for Innovative Drug Evaluation and Research,Guangzhou 510900 Guangdong,China)
出处
《中药新药与临床药理》
CAS
CSCD
北大核心
2024年第7期1093-1100,共8页
Traditional Chinese Drug Research and Clinical Pharmacology
基金
广东省实验室建设项目(2023B1212070029)
广东省重大人才工程项目(210183503006)。
关键词
连翘
化学成分
药理作用
安全性评价
Forsythiae fructus
chemical composition
pharmacological action
safety evaluation
