中国胰腺癌病理取材及诊断报告规范循证学指南

Evidence-based guidelines for standardized pathologic sampling and diagnosis reporting of pancreatic cancer in China

胰腺癌标本的病理学分析最主要的目的是通过评估肿瘤的组织学类型、分化程度、肿瘤大小、浸润范围、切缘状态等以评估肿瘤的分期及预后,而完成精准评估的首要前提就是病理取材的细致和全面。本指南就胰腺癌病理取材、切缘定义、结构化报告内容和诊断要点等形成共识,旨在促进我国胰腺癌取材及诊断报告的规范化、精准化,提高病理医师精准诊断的能力,为临床提供切实有效的评估预后的病理学参数,从而为患者后续治疗方案的制订提供有力的依据。同时标准化的肿瘤数据收集也将为流行病学专家提供信息,有助于国内及国际规范的制定及研究。

The main purpose of pathological analysis of pancreatic cancer(PC)specimens is to assess the tumor stage and predict the prognosis by evaluating the histological type,degree of differentiation,tumor size,depth of invasion,surgical margin status and the like.Careful,standardized and comprehensive pathological specimen sampling is prerequisite for accurate assessment.This guideline compiles a consensus on pathological sampling,definition of surgical margins,content and diagnostic points of structured report for PC after discussion,aiming to improve the standardization and precision of PC specimen sampling and diagnostic reports in our country,and enhance the precision diagnostic ability of pathologists.These provide clinicians with practical and effective pathologic parameters for prognosis assessment,thereby providing strong support for the formulation of treatment strategies for patients after surgery.Standardized oncology data collection also provides information for epidemiologists,which contributes to national and international standardization and research.