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卵巢衰老的机制与治疗策略

Mechanisms and treatment strategies of ovarian aging
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摘要 卵巢作为女性的重要生殖器官在维持生殖健康和生活质量中具有重要作用。卵巢衰老是指卵巢功能下降直至最终衰竭的过程,不仅会导致女性生育能力的下降,而且还会加速女性衰老并引起一系列相关疾病,严重威胁女性生殖健康和生活质量。因此,阐明卵巢衰老的机制并进一步探究卵巢的抗衰老策略,对减缓卵巢衰老和保持女性生育力具有重要意义。本综述回顾分析了国内外卵巢衰老相关研究,总结了当前卵巢衰老的相关机制并提出了相应的预防和治疗策略。 As an important reproductive organ in women,ovary plays a vital role in maintaining reproductive health and quality of life.Ovarian aging refers to the decline of ovarian function and eventually failure,which not only leads to the decline of female fertility,but also accelerates female aging and causes a series of related diseases,which seriously threatens female reproductive health and quality of life.Therefore,elucidating the mechanism of ovarian aging and further exploring the anti-aging strategies of the ovary are of great significance for slowing down ovarian aging and maintaining female fertility.This article reviews and analyzes the relevant studies of ovarian aging at home and abroad,summarizes the relevant mechanisms of ovarian aging and puts forward the corresponding prevention and treatment strategies.
作者 何甜甜 许博 杜星 付旭锋 He Tiantian;Xu Bo;Du Xing;Fu Xufeng(Key Laboratory of Fertility Maintenance,Ministry of Education,Ningxia Medical University,Yinchuan 750000,China)
出处 《中华生殖与避孕杂志》 CAS CSCD 北大核心 2024年第7期755-758,共4页 Chinese Journal of Reproduction and Contraception
基金 国家自然科学基金(81960270)。
关键词 卵巢颗粒细胞 卵巢衰老 抗衰老 Ovarian granulosa cells Ovarian aging Anti-aging
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