从“燥湿同病”论治干燥综合征型干眼

Treating Sjögren's Syndrome-Related Dry Eye Disease Based on the Theory of"Disease Involving both Dryness and Dampness"

“燥湿同病”理论认为,疾病可由燥邪和湿邪相互夹杂、胶着所引起,形成燥中有湿、湿中有燥的病理状态,两者可相伴而生、相互转化、并存为病。从干燥综合征型干眼(SS-DED)的临床特点出发,认为其症状可以反映出燥湿并存的病理状态,燥湿并存为SS-DED的关键病机,以补泻兼施、燥湿同治为主要治则。治疗应注重理气健脾祛湿、开腠养阴润燥,临证予以沙参麦冬汤合香砂六君子汤加减治之。从“燥湿同病”论治SS-DED,以期为该病的临床诊疗提供思路。

Based on the theory of"disease involving both dryness and dampness",it is believed that the complex of dryness and dampness and the mutual stalemate between them produce the disease,forming a pathological state of dampness within dryness and dryness within dampness.The two can occur accompanied by each other,transform into each other,and coexist as a disease.According to the clinical characteristics of sjögren's syndrome-related dry eye disease(SS-DED),it is believed that its symptoms can reflect the pathological state of coexistence of dryness and dampness,and that"disease involving both dryness and dampness"is the key pathogenesis.The main treatment principles are performing both purgation and tonification,and treating the dryness and dampness simultaneously.The treatment should focus on rectifying qi,fortifying spleen and dispelling dampness,as well as opening orifices,nourishing yin and moistening dryness,usually with Shashen Maidong Decoction(沙参麦冬汤)and Xiangsha Liujunzi Decoction(香砂六君子汤)in modifications.The theory of"disease involving both dryness and dampness"is expected to provide ideas for the diagnosis and treatment of SS-DED.