基于子午流注理论指导刮痧治疗阴虚阳亢型Ⅰ级原发性高血压的疗效及对血清HCY、CRP的影响

Efficacy of Guasha therapy guided by the Meridian Flow Theory on GradeⅠ primary hypertension of Yin deficiency and Yang hyperactivity type and its effects on serum HCY and CRP levels

目的探究基于子午流注理论指导刮痧治疗阴虚阳亢型I级原发性高血压的疗效及对血清同型半胱氨酸(HCY)、C反应蛋白(CRP)的影响。方法选取2019年12月1日至2021年12月31日期间就诊的阴虚阳亢型I级原发性高血压患者58例作为研究对象。以数字随机表法分成研究组与对照组,每组患者29例,对照组以常规生活方式进行干预,研究组在对照组的常规生活方式干预的基础上加用基于子午流注理论指导刮痧的方式治疗,两组患者连续治疗3个月后,比较两组患者的治疗效果及对血清HCY、CRP的影响。结果治疗后,研究组患者在眩晕、失眠、耳鸣、五心烦热、腰膝酸软症状相较于治疗前均得到明显改善(P<0.05);与对照组比较,研究组患者治疗后的中医症状明显得到改善(P<0.05)。治疗后,两组患者的舒张压与收缩压均有所降低,且研究组患者的舒张压与收缩压明显低于对照组;与治疗前比较,研究组患者的舒张压与收缩压明显低于治疗前(P<0.05)。治疗后,两组患者的血清CRP、HCY水平均降低,且相较于对照组,研究组患者的血清CRP、HCY水平降低的程度更明显(P<0.05)。治疗后,两组患者的杜氏高血压生活质量量表中各维度的评分均升高,且研究组患者的杜氏高血压生活质量量表中各维度评分升高的更明显(P<0.05);与治疗前比较,治疗后两组患者的杜氏高血压生活质量量表中各维度的评分均明显提升(P<0.05)。结论基于子午流注理论的指导刮痧治疗阴虚阳亢型级EH患者能降低其血压水平及CRP、HCY指标水平,缓解其中医症状,并能提高其生活质量,起到标本兼治的作用,安全性高,值得在临床上推广。

Objective To explore the efficacy of Gua Sha therapy guided by the Meridian Flow Theory in the treatment of Grade I primary hypertension of Yin deficiency and Yang hyperactivity type,and its effects on serum homocysteine(HCY)and C-reactive protein(CRP)levels.Methods Ffty-eight patients with Grade I primary hypertension of Yin deficiency and Yang hyperactivity type,who were treated in our hospital from December 1,2019,to December 31,2021,were selected for this study.Using a digital random table method,the patients were divided into a study group and a control group,with 29 patients in each group.The control group received conventional lifestyle interventions,while the study group received Gua Sha therapy guided by the Meridian Flow Theory in addition to the conventional lifestyle interventions.After three months of continuous treatment,the therapeutic effects and the impact on serum HCY and CRP levels were compared between the two groups.Results After treatment,the symptoms of dizziness,insomnia,tinnitus,five-heart vexing heat,and soreness and weakness in the lumbar and knees in the study group were significantly improved compared to before treatment(P<0.05).Compared with the control group,the study group's traditional Chinese medicine(TCM)symptoms showed significant improvement after treatment(P<0.05).After treatment,both groups showed reductions in diastolic and systolic blood pressure,with the study group exhibiting significantly lower diastolic and systolic blood pressure than the control group(P<0.05).Additionally,serum CRP and HCY levels decreased in both groups after treatment,with the study group showing a more pronounced reduction compared to the control group(P<0.05).Furthermore,the scores of the Dusi Hypertension Quality of Life Scale in all dimensions increased in both groups after treatment,with the study group showing a more significant increase(P<0.05).Compared to before treatment,the scores of the Dusi Hypertension Quality of Life Scale in all dimensions were significantly improved in both groups after treatment(P<0.05).Conclusion Gua Sha therapy guided by the Meridian Flow Theory for patients with Grade I primary hypertension of Yin deficiency and Yang hyperactivity type can reduce blood pressure and serum CRP and HCY levels,alleviate TCM symptoms,and improve quality of life.It has a high safety profile and is worthy of clinical promotion.