糖尿病酮症酸中毒患者应用胰岛素泵治疗的效果

Effect of Insulin Pump Therapy in Patients with Diabetic Ketoacidosis

目的分析糖尿病酮症酸中毒患者应用胰岛素泵治疗的效果。方法选取2020年1月至2023年6月期间于瑞金市人民医院接受治疗的56例糖尿病酮症酸中毒患者为本次研究对象,随机分为研究组和对照组,每组各28例。研究组用胰岛素泵,对照组接受常规皮下注射胰岛素的治疗方案,统计分析两组患者治疗相关指标、不良反应总发生率和治疗总有效率。结果治疗后研究组控糖所需时间、控糖所需胰岛素、尿酮转阴时间、尿酮转阴所需胰岛素等各项指标均明显低于对照组,组间差异有统计学意义(P<0.05);研究组不良反应总发生率明显低于对照组,研究组治疗总有效率明显高于对照组,组间差异有统计学意义(P<0.05)。结论胰岛素泵可更好地控制输液速度和血液中药物浓度且具有流速稳定、定时准确度高等优点,不仅可降低不良事件发生,还能避免血糖迅速下降造成的低血糖现象。

Objective To analyze the effect of insulin pump treatment on diabetic ketoacidosis patients.Methods A total of 56 patients with diabetic ketoacidosis treated in Ruijin People's Hospital from January 2020 to June 2023 were randomly selected as the objects,were randomly divided into study group and control group,with 28 patients in each group.The study group used insulin pump,and the control group received conventional subcutaneous insulin injection treatment.The treatment-related indicators,the total incidence of adverse reactions and the total effective rate of treatment of the two groups were statistically analyzed.Results After treatment,the time required for glucose control,the insulin required for glucose control,the time for urine ketone to turn negative,and the insulin required for urine ketone to turn negative were significantly lower in the study group than in the control group,with statistically significant differences between the two groups(P<0.05);the total incidence of adverse reactions in the study group was significantly lower than that in the control group,and the total effective rate of treatment in the study group was significantly higher than that in the control group,with statistically significant differences between the two groups(P<0.05).Conclusion Insulin pump can better control the infusion speed and drug concentration in blood,and has the advantages of stable flow rate and high timing accuracy.It can not only reduce the occurrence of adverse events,but also avoid hypoglycemia caused by rapid decrease in blood glucose.