基于卫气营血辨证病毒性上呼吸道感染老年患者转归

Prognosis of elderly patients with viral upper respiratory tract infection based on Weiqi Yingxue differentiation

目的通过对老年病毒性上呼吸道感染患者数据分析,探讨卫气营血临床症状与上呼吸道病毒感染老年患者预后之间的相关性。方法收集2021年10月—2023年5月在上海市第六人民医院中医科收治的年龄≥60岁急性病毒性呼吸道感染患者749例,采用Excel云问卷进行调查,包括患者基本资料、合并基础疾病、中医临床症状、运动强度、当年是否接种流感疫苗等,结合病历库中患者临床症状缓解天数等汇总后建立数据库,分析患者卫气营血相关中医临床症状,人口基本特征,当年流感疫苗接种与否,合并基础疾病等与临床症状缓解时间的关系。结果男性和女性在吸烟饮酒情况、体育运动情况上,差异均有统计学意义(P<0.05);比较不同中医临床症状患者的临床症状缓解时间发现,有发热、鼻塞、咽干咽痛、咳嗽、肢体酸痛等症状的患者临床症状缓解天数均高于无相应证候的患者,差异有统计学意义(P<0.05);合并基础疾病分析发现有慢性胃炎、骨性关节炎的患者临床症状缓解天数高于无相应慢性基础疾病的患者,差异有统计学意义(P<0.05)。结论表现有中医临床症状(发热、鼻塞、咽干咽痛、咳嗽、肢体酸痛)以及既往慢性基础疾病(慢性胃炎、骨性关节炎)的老年急性上呼吸道感染患者,临床症状缓解天数较无相关中医临床症状及无相应慢性基础疾病的患者长,提示卫气营血状态与上呼吸道病毒感染患者的预后之间可能存在相关性,为后续进一步指导临床老年呼吸道病毒性感染疾病防治提供依据。

Objective To explore the correlation between the clinical symptoms of WeiqiYingxue and the prognosis of elderly patients with viral upper respiratory tract infectionby analyzing the data of elderly patients with viral upper respiratory tract infection.Methods 749 patients aged≥60 years old with acute viral respiratory tract infection admitted to Department of Traditional Chinese Medicine of Sixth People s Hospital of Shanghai City from October 2021 to May 2023 were collected.Excel cloud questionnaire was used to investigate the patients,including basic information,combined underlying diseases,clinical symptoms of traditional Chinese medicine(TCM),exercise intensity,and whether they had received influenza vaccine in the same year.A database was established after summarizing the clinical symptom relief days of patients in the medical record database.The relationship between TCM clinical symptoms related to Weiqi Yingxue,basic characteristics of population,influenza vaccination or not in the same year,combined underlying diseases and the clinical symptom relief time were analyzed.Results There were statistically significant differences between males and females in smoking,drinking,and physical activity(P<0.05).Comparing the clinical symptom relief time of patients with different TCM clinical symptoms,it was found that patients with symptoms such as fever,nasal congestion,dry throat,sore throat,cough,and limb pain had a significantly longer clinical symptom relief time than patients without corresponding symptoms,and the differences were statistically significant(P<0.05).The analysis of combined underlying diseases found that patients with chronic gastritis and osteoarthritis had a longer clinical symptom relief time than those without corresponding combined underlying diseases,and the differences were statistically significant(P<0.05).Conclusion Elderly patients with acute upper respiratory tract infections who exhibit TCM clinical symptoms(fever,nasal congestion,dry throat,sore throat,cough,limb soreness)as well as previous chronic underlying diseases(chronic gastritis,osteoarthritis)have alonger clinical symptom relief timethan patients without above symptoms or corresponding chronic underlying diseases.It is suggested that there may be a correlation between the state of Weiqi Yingxue and the prognosis of elderly patients with viral upper respiratory tract infection,which provides a basis for further guidance on the prevention and treatment of elderly patients with viral upper respiratory tract infection.