以药师为主导的药学干预模式对肺炎患儿发生抗生素相关性腹泻的影响

Effect of pharmacist led pharmaceutical intervention model on antibiotic related diarrhea in children with pneumonia

目的探讨以药师为主导的药学干预对肺炎患儿发生抗生素相关性腹泻的影响。方法选取2022年8月至2023年8月滕州市中心人民医院收治的110例肺炎患儿作为研究对象,按照奇偶数法将其分到参照组、试验组。参照组(n=55)采取常规药学服务,试验组(n=55)采取以药师为主导的药学干预模式,比较两组广谱抗生素使用率、抗生素相关性腹泻发生率、抗生素应用时间、细菌培养标本送检率等。结果试验组广谱抗生素使用率、抗生素相关性腹泻发生率低于参照组,抗生素使用时间短于参照组,细菌培养标本送检率高于参照组,差异有统计学意义(P<0.05)。结论以药师为主导的药学干预模式应用于肺炎患儿治疗中,可降低抗生素相关性腹泻发生率,规范抗生素的使用。

Objective To explore the effect of pharmacist led pharmaceutical intervention model on antibiotic related diarrhea in children with pneumonia.Methods A total of 110 children with pneumonia admitted to Tengzhou Central People’s Hospital from August 2022 to August 2023 were selected as the study samples.They were divided into reference group and experimental group according to the odd-even method.The reference group(n=55)received routine pharmaceutical services,while the experimental group(n=55)received pharmacist led pharmaceutical intervention model.The utilization rate of broad-spectrum antibiotics,the incidence of antibiotic related diarrhea,the duration of antibiotic application,and the detection rate of bacterial culture samples were compared between the two groups.Results The utilization rate of broad-spectrum antibiotics and the incidence of antibiotic related diarrhea in the experimental group were lower than those in the control group,and the duration of antibiotic use was shorter than that in the control group,the detection rate of bacterial culture samples was higher than that in the control group,the differences were statistically significant(P<0.05).Conclusion The application of pharmacist led pharmaceutical intervention model in the treatment of children with pneumonia can reduce the incidence of antibiotic related diarrhea and standardize the us e of antibiotics.